Thoon Koh Cheng
Adj Assoc Prof Thoon Koh Cheng
KK Women's and Children's Hospital
Medicine: Dept of Paediatrics, Infectious Disease Service
Head & Senior Consultant
MBBS(Melbourne), MMed (S’pore), MRCPCH (UK)

Dr Thoon Koh Cheng obtained his postgraduate General Paediatrics qualifications from RCPCH as well as NUS in 2004. He trained in Paediatric Infectious Diseases at the Hospital for Sick Children in Toronto in 2007, and recently was appointed as Head of Infectious Disease Service in June 2010. He is also an Adjunct Instructor at YLL School of Medicine, and Adjunct Assistant Professor at Duke-NUS Graduate Medical School. He sits on multiple Department and Hospital level committees, as well as MOH Committees including the Expert Committee on Immunisation and the National Antimicrobial Taskforce. He was instrumental in developing the KKH Paediatric Dengue Fever guidelines, KKH Infectious Disease System, the KKH Vaccine Pocketbook, and piloted the 1st National inpatient active vaccine adverse event surveillance. He is involved in multiple research trials, though his main research interests are in Mycobacterial Infections (TB and NTM), vaccine preventable diseases, severe invasive bacterial and viral diseases, HIV and Dengue.


  • MBBS, The University of Melbourne 

    • 1998


  • MRCPCH, Royal College of Paediatrics and Child Health, UK 

    • 2004


  • Master of Medicine (Paediatrics), National University of Singapore 

    • 2003

Professional Appointments and Committee Memberships

  • Head/Consultant, Department of Paediatrics, Infectious Disease 

    • 2010-present


  • Adjunct Instructor- Undergraduate Medical Education Director, YLL SOM, NUS


  • Adjunct Instructor, Duke-NUS Graduate Medical School Singapore (GMS)


  • Adjunct Assistant Professor, Duke-NUS GMS


  • Member, Singapore Medical Association 

    • 2000-present


  • Member, Society of Infectious Diseases Singapore 

    • 2006-present


  • Member, European Society of Paediatric Infectious Diseases 

    • 2009-present


  • Member, National Antimicrobial Taskforce (NAT), Antimicrobial Utilization and Stewardship (AUS) Workgroup, 

    • MOH 2009-present


  • Member, Expert Committee on Immunisation, MOH 2010-2013


  • Member, Workgroup for Review of Health Booklet, School Health Service 

    • 2010-present


  • National Innovation Quality Circle (NIQC), Gold Award 

    • 2010


  • MOH Healthcare Quality Improvement Poster Competition, Merit 

    • 2010


  • KKH 20th Process Improvement Forum, Gold Award 

    • 2010


  • Long Service Award, KKH 

    • 2010


  • Human Manpower Development Program, MOH 

    • 2007

Publications and Research Trials



  1. Infectious Diseases. In: Puthucheary J, Tan TH, Phua KB, Tan CL (eds). The Baby Bear Book, A Practical Guide on Paediatrics (2nd Ed). Singapore: KK Women's and Children's Hospital; 2010:304-340

  2. KC Thoon, CY Chong, WYM Ng, PE Kilgore, B Nyambat. Epidemiology of invasive Haemophilus influenzae type b disease in Singapore children, 1994-2003. Vaccine 2007;25(35):6482-6489

  3. CY Chong, KC Thoon, YH Mok, NWS Tee. Invasive Pneumococcal disease in Singapore children. Vaccine 2008;26(27-28):3427-3431

  4. KC Thoon, CY Chong. Survey of Healthcare-Worker Attitudes, Beliefs and Willingness to Receive Pandemic (H1N1) 2009 Influenza A Vaccine and the Impact of Educational Campaigns. Ann Acad Med Singapore 2010;39(4):307-312

  5. KC Thoon, CY Chong, Seet CMJ. KK Women’s and Children’s Hospital Vaccine Pocketbook for Healthcare Professionals. Singapore: Singhealth Academy; 2011.




  1. Immunogenicity and large-scale safety of Tetravalent Dengue Vaccine in healthy subjects aged 2 to 45 in Singapore- Multicenter, Observer-blind for the first and second vaccinations and Single-blind for the third one, Randomized, Controlled, Phase II trial in 1200 subjects. Three Vaccinations over a period of 1 year, with a 4-year follow-up after the last

  2. Epidemiology of Tuberculosis Disease in Singapore Children, a Single Centre Experience from 1997 to 2009

  3. HSA-KKH Inpatient Surveillance of Post-vaccination Reactions (HK-InSPiRE)

  4. Trends in Invasive Pneumococcal Disease in Singapore children, 2005-2015

  5. Estimates of clinical burden of influenza in children


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