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Drug Class: Commonly Known As: Category:
Topoisomerase I Inhibitor Cancer-related

Irinotecan - What is it for

​Irinotecan is a chemotherapy drug that may be used alone or together with other drugs to treat certain types of cancer.

Irinotecan - Side Effects, Precautions, and Contraindications

What side effects can Irinotecan cause?

Early side effects

  • Abdominal cramping, sweating, diarrhea, watery eyes, visual disturbances, or increased salivation
    Atropine injection will be given before treatment to reduce such symptoms.
  • Nausea and vomiting
    There are medications available which may prevent or decrease these side effects. If you are given these medications, take them as directed.
  • General weakness

Delayed side effects

  • A drop in the blood cell counts may occur several days after treatment
  • Temporary hair loss

Please seek medical attention if any of the following occurs:

  • Fever of 38°C or higher.
  • Severe diarrhea not resolved with appropriate anti-diarrheal medication
  • Unusual bleeding, bruising or black sticky stools
  • Dizziness that persist for more than 3 days
  • Persistent dry cough or shortness of breath

Before taking Irinotecan, what precautions must I follow?

What food or medicine must I avoid when I take Irinotecan?

Irinotecan - Dosage and How to Use

How should Irinotecan be used?

What should I do if I miss a dose?

What should I do if I overdose?

Irinotecan - Handling

How should I handle Irinotecan safely?

Irinotecan - Storage

How should I store Irinotecan?

How should I dispose of Irinotecan safely?

Irinotecan - Additional Information

  • Updated on Tuesday, August 21, 2018
  • Article contributed by Department of Pharmacy National Cancer Centre Singapore

    The information provided is not intended as medical advice. Terms of use. Information provided by SingHealth

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