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Dr Lee Cia Sin

Dr Lee Cia Sin

​MBBS, MMed (Fam Med), FCFP (Singapore)


Family Physician

Specialty: Family Medicine

Clinical Appointments

  • Consultant

Academic Appointments

  • Adjunct Senior Lecturer, Lee Kong Chian School of Medicine, NTU
  • Clinical Assistant Professor, Duke NUS Medical School


Dr Lee Cia Sin is a Consultant Family Physician at the Singhealth Polyclinics. She received her medical degree from the University of Malaya (Malaysia) in 2008, her Master of Medicine (Family Medicine) from National University of Singapore in 2012, as well as her Fellowship of the College of Family Physician (FCFP) in 2017.

Her clinical and research interests are in the area of diabetes, geriatric medicine and health services research. Dr Lee also published in respectable peer-reviewed journals (such as in the Annals of Family Medicine). Currently, she is the site principal investigator for the OPTIMUM trial (Optimizing care of Patients via Telehealth In Monitoring and Augmenting their control of Diabetes Mellitus), which is a randomized controlled trial funded by the MOH Office for Healthcare Transformation to design a new model of care for the future primary care setting. She also teaches medical students at Duke-NUS and Nanyang Technological University.


  • ​• FCFP(S) (2017) 
    • Mmed - Family Medicine (2012)
    • MBBS (2008)

Professional Appointments and Committee Memberships

  • Member, College of Family Physician Singapore


Research Interests

​• Diabetes Mellitus
• Potentially inappropriate prescribing in older adults
• Health service research


• The prevalence and impact of potentially inappropriate prescribing among older persons in primary care settings: multilevel meta-analysis. TM Liew, CS Lee, SKL Goh, ZY Chang. Age and Ageing. 2020 Jul. 46 (4), 570-579. doi:10.1093/ageing/afaa057. PMID: 32365168.
• Potentially Inappropriate Prescribing Among Older Persons: A Meta-Analysis of Observational Studies. TM Liew, CS Lee,  SKL Goh, ZY Chang. Ann Fam Med 2019;17:257-266. PMID: 31085530.
• Reappraising the Efficacy and Acceptability of Multicomponent Interventions for Caregiver Depression in Dementia: The Utility of Network Meta-Analysis. Gerontologist. Liew TM, Lee CS.  2019 Jul 16;59 (4): e380-e392. doi: 10.1093/geront/gny061. PMID: 29860310.
• Comparative efficacy and acceptability of interventions for major depression in older persons: protocol for Bayesian network meta-analysis. Liew TM, Lee CS.  BMJ Open. 2018 Jan 21;8(1):e019819. doi: 10.1136/bmjopen-2017-019819. PubMed PMID: 29358451.
• Assessing oral medication adherence among patients with type 2 diabetes mellitus treated with polytherapy in a developed Asian community: a cross-sectional study. Lee CS, Tan JHM, Sankari U, Koh YLE, Tan NC.  BMJ Open. 2017 Sep 14;7(9):e016317. doi: 10.1136/bmjopen-2017-016317. PubMed PMID: 28912194; PubMed Central PMCID: PMC5640112
• Inappropriate prescribing among older persons in primary care: protocol for systematic review and meta-analysis of observational studies. Lee CS, Liew TM. BMJ Open. 2017 Feb 24;7(2):e015395. doi: 10.1136/bmjopen-2016-015395. PMID: 28237963

Research Trials

• Site PI: Optimizing care of Patients via Telehealth In Monitoring and Augmenting their control of Diabetes Mellitus (OPTIMUM)
• Co-I: Assessing the risk of coronary artery disease and its association with anxiety disorders amongst patients presenting with chest pain in a primary healthcare setting: a comparison of 3 predictive models
• Co-I: Management of Hypertension and Multiple Risk Factors to Enhance Cardiovascular Health - A Cluster Randomized Trial in SingHealth Polyclinics, Singapore
• Co-I: Raising Awareness of Pneumococcal Vaccination Amongst Elderly Patients Above 65 Years Old Attending Singhealth Polyclinic - A Community Health Project
• PI: Factor Influencing Drug Adherence among patients with type 2 Diabetes Mellitus (FInD A DM)