Dr Ivy Ho received her Ph.D. from the National University of Singapore in the field of viral gene therapy for glioma. She continued her postdoctoral training on mesenchymal stem cells studying their migration and role in cancer therapy at the National Cancer Centre of Singapore. Her findings suggested a role of mesenchymal stem cells in modulating the tumour stroma microenvironment that inhibited glioma progression.

She is currently a Principal Investigator and heads the Molecular Neurotherapeutics Laboratory at the National Neuroscience Institute. Her long-time interest in brain tumour therapy has led her to focus on understanding the intrinsic and microenvironmental factors that could impact glioma therapy.

In particular, the lab is investigating how reciprocal communication between glioma cells and the immune microenvironment influences glioma invasion and mesenchymal transition. In connection with glioma invasiveness, her laboratory also investigates the role of the NF1 tumour suppressor gene in neuroblastoma metastasis.