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Dr Ryan Lee Wai Kheong

Dr Lee Wai Kheong Ryan

MBBS (UK), BSc (Hons), MMed (O&G), MRCOG (UK), MCI (Spore)


KK Women's and Children's Hospital

Specialty: Maternal Fetal Medicine, General Obstetrics and Gynaecology

Sub-specialties: Obstetric Medical Disorders

Conditions Treated by this Doctor:
Ectopic Pregnancy, Family Planning, Fibroids, Fibroids of the uterus, General Obstetrics & Gynaecology, Gestational Diabetes Mellitus (GDM), High Risk Obstetrics, Medical Disorders in Pregnancy and other Pregnancy Complications, Menopause, Menorrhagia, Multiple Pregnancies, Ovarian Cysts, Polycystic Ovarian Syndrome, Pregnancy Care During Pregnancy, Pregnancy Labour and Delivery.

Clinical Appointments

  • Consultant Department of Maternal Fetal Medicine KK Women's and Children's HospitalKK Women's and Children's Hospital


Dr Ryan Lee is a Consultant Obstetrician and Gynaecologist at the Department of Maternal-Fetal Medicine, Division of Obstetrics and Gynaecology. He graduated with an intercalated bachelor of medical science degree (Honours) at Imperial College London in 2008 and obtained MBBS (Distinction) in Medical Sciences, Clinical Science and Clinical Practice at St Bartholomews and the Royal London, University of London in 2009. He later obtained Masters of Medicine (O&G) and was conferred a member of the Royal College of Obstetrics and Gynaecology (MRCOG) in 2015. Subsequently, he graduated from the Clinician-Scientist residency in 2018 and became a fully qualified Obstetrician and Gynaecologist with the Specialist Accreditation Board of the Ministry of Health, Singapore in 2019.

Dr Lee advocates a holistic approach to the care of pregnant mothers through optimisation of medical conditions in pregnancy to achieve the best outcomes for mothers and their babies. His current clinical practice encompasses high risk obstetrics with special interest in maternal medicine where he runs the Obstetric High-Risk Clinics (STORK) to optimise pregnant mothers for antenatal, peripartum and postpartum care.

Dr Lee’s main research interests focuses on interventional lifestyle changes in improving obstetric outcomes in women with gestational diabetes and enhancing pregnancy outcomes in sub-fertile women with recurrent implantation failure. He is an Integrated Platform for Research in Advancing Metabolic Health Outcomes in Women and Children (IPRAMHO) investigator to develop excellent models of metabolic care to reduce obesity and diabetes in women. He was previously awarded the NMRC health research scholarship in 2016 to study the role of endometrial stem cells in women with recurrent implantation failure, graduating with a Masters of Clinical Investigation from the National University of Singapore in 2018. He presented in numerous international conferences and published numerous papers in reputable peer reviewed journals.

Besides research, he has an incessant passion for teaching and was previously awarded the inspiring Resident-Educator award. He is currently appointed as a SingHealth residency physician facilitator and clinical tutor to students from Duke-NUS, YLL and LKC School of Medicine where he continues to receive commendable accolades from his students. He is married with 2 children whom he cherishes spending quality time with together.


  • Masters of Clinical Investigation (NUS) 2018
  • Masters of Medicine (O&G) 2015
  • MRCOG (UK) 2015
  • St Bartholomew’s and the Royal London, Queen Mary, University of London, UK (MBBS) 2009
  • Imperial College London (BSc reproductive and developmental sciences) (Hons) 2008

Professional Appointments and Committee Memberships

  • Associate Consultant, Department of Maternal Fetal Medicine, KK Women's and Children's Hospital 2019 – 2021
  • Physician Faculty Member, SingHealth Obstetrics and Gynaecology Residency Programme
  • Adjunct Instructor, Clinical Teacher, SingHealth-Duke NUS Medical School
  • Clinical Tutor, Yong Loo Lin School of Medicine (NUS)
  • TBL and Content Expert, Clinical Teacher, Lee Kong Chian School of Medicine
  • Member, Obstetrical and Gynaecological Society Singapore (OGSS)
  • Member, Integrated Platform for Research in Advancing Metabolic Health Outcomes in Women and Children (IPRAMHO) Study Group
  • Member, Healthy Early Life Moments in Singapore (HELMS)
  • Research Fellow, SingHealth-Duke NUS Medical School


  • KKH Long Service 10-year Award 2021
  • SingHealth Community Care Facilities (CCF) best team award 2021 for ‘COVID-19’ contribution
  • Singapore Health Quality Service Silver award 2019
  • ASPIRE best poster presentation 2019
  • NMRC research scholarship (MCI) 2016
  • SingHealth RISE Young Educator Award 2013
  • MOH training award 2012
  • MBBS triple distinctions (medical sciences, clinical sciences, and clinical practice) 2009
  • Harvey Minasian Prize (co-winner) 2008
  • Barts And The London Association Elective Travel Award (BATLAA) 2008
  • Kirkes Scholarship for outstanding academic achievement 2007
  • Ian Howat and Georges Burrow Prize in Pathology 2007
  • CHRAT Summer Vacation Research Studentship Award 2006

Research Interests

  • Gestational diabetes
  • Micronutrients in pregnancy
  • Recurrent Implantation failure and endometrial stem cells


  • Working Summer. Ryan Lee, S Tso. Student BMJ July 2007 ;15:257-292
  • Plasma biomarker discovery in pre-eclampsia using a novel differential isolation technology for circulating extracellular vesicles. KH Tan, SS Tan, Newman SK, WKR Lee et al. Am J Obstet Gynecol 2014.pii: S0002-9378(14)00248-8
  • An Unusual Case of Acquired Uterine Arteriovenous Malformation With Persistent Scar Ectopic Pregnancy Successfully Managed With Uterine Artery Embolization. Visvalingam G , WKR Lee, TY Tan, HH Tan . Journal of medical cases 2016, 7(4):143-147, DOI: 10.14740/jmc2458w
  • Primary malignant mixed Müllerian tumour (MMMT) of the vagina and review of the literature. Visvalingam G, WKR Lee, Wong CF , YK Lim . Case Reports BMJ, 2016 , DOI: 10.1136/bcr-2016-214856
  • A case of ruptured ovarian ectopic after embryo transfer with low serum hCG and fertility conserving laparoscopy. WKR Lee, Nadarajah S. Journal of medical cases 7(4):150-152, 2016, DOI: 10.14740/jmc2464w
  • A rare case of primary angiosarcoma of ovary in a post menopausal woman. Bhutia K, JJ Wang, Siraj, WKR Lee, et al. Journal of Medical cases 2017.
  • A Case of Ovarian Glomus Tumor and Literature Review. WKR Lee, Lim JZ , et al, YK Lim. Journal Of medical cases 2018 .ISSN 1923-4155 .1923-4163
  • Undiagnosed abdominal term pregnancy with good neonatal outcome. Phoy CC, KH Chua, et al ,WKR LEE. Case reports in Obstetrics & Gynaecology 2019. Article ID 2460485
  • Ovarian biomarkers predict controlled ovarian stimulation for In vitro fertilization treatment Singapore. Lee RWK, LW Khin, et al, J Chan. Singapore Med J 2020;61(9):463-468
  • Attitude and precaution perceptions towards COVID-19 among pregnant women in Singapore. Lee RWK, See Ling Loy et al, LK Tan.BMC pregnancy childbirth 2020 Nov10;20(1) 675
  • Asia-Pacific consensus on physical activity and exercise in pregnancy and the postpartum period. Lee R, Thain S, Tan LK IPRAMHO Exercise in Pregnancy Committee, et al BMJ Open Sport & Exercise Medicine 2021;7:e000967.
  • MOH/COGS guidelines on ‘Medical termination of pregnancy’ June 2020. Under MOH review

Research Trials

  • The effect of local endometrial injury on women with repeated implantation failure in women undergoing in-vitro fertilization - KKHHEF fund
  • The role of endometrial stem cells in women with recurrent implantation failure - National Medical Research Council Seed fund Grant
  • Lifestyle interventions to prevent postpartum type 2 diabetes in Asian women with a history of gestational diabetes mellitus (LCG grant)
  • Oral health, oral microbiome and salivary immunome in gestational diabetes mellitus (NIG grant)