Participants will undergo eligibility screening, which may include a baseline screening cooked egg challenge, to confirm current egg allergy. If found to be eligible, participants will be randomly allocated to one of two groups:
Control. This means participants will be assigned to one of the two groups below by chance.
The study will be conducted at KK Women’s and Children’s Hospital (KKH). Total OIT treatment period will last between 12 and 18 months. Apart from hospital visits for all food challenges, participants in the active group will be required to visit the hospital for pancake/cookie dose initiation; and every 4 weeks subsequently for pancake dose increments (a total of about 9 to 11 visits to KKH throughout the study duration). Clinical data will be collected during all hospital visits. Skin prick tests and blood samples will be collected at screening and before the cooked egg challenges at the end of treatment.
Costs of therapy and clinical investigations will be borne by participants, but transport reimbursement will be given on completion of each scheduled visit.
Principal Investigator: Dr Chong Kok Wee
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