Macitentan

• Do not stop taking your medication without checking with your healthcare professional as it may make your condition worse.
• You may take this medication with or without food. 
• This medication is initially started at a lower dose. Your condition will be monitored closely. Your doctor may later adjust your dosage to better control your condition.

If you forget to take a dose, take it as soon as you remember. If it is almost time for your next dose, skip the missed dose. Then take your next dose at the usual time. Do not take two doses to make up for the missed dose.