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Transplant & Leukemia Survival Rates (1997-2014)

The Children’s Cancer Centre in KKH is one of the largest paediatric cancer centres in South-East Asia, treating 70% of childhood cancers in Singapore. Each year, the centre sees between 110-130 paediatric cancer cases of which 40% have leukaemia.

Childhood cancer is the second major cause of death among children in Singapore. There are between 180 and 200 newly diagnosed cases of cancer in Singapore each year. Acute Lymphoblastic leukemia (ALL) is the most common malignancy in children and adolescents.

Here at KKH, the outcome for ALL has climbed steadily from 40% in the 80’s to 60% in the 90’s and 80% in 2000’s. Present chemotherapy regime produces a five-year overall survival and event-free survival of 92% and 82%. This is comparable with world-renowned children cancer centres. Collaborative studies between KKH, NUH and University of Malaya are on-going to refine the protocols to decrease treatment in those with standard risk ALL to minimize late effects of treatment, while those with high risk ALL requires consolidation treatment, which includes allogeneic haemapoietic stem transplant.

Our Children’s Cancer Centre also uses allogeneic haematopoietic stem cell transplant as a form of treatment for the following diseases:

  • Lymphoma
  • Neuroblastoma
  • Sarcoma
  • Malignant and non-malignant blood disorders
  • Immunodeficiencies

Our survival rates for allogeneic haematopoietic stem cell transplant stands at 68%. These are comparable to the best centers in the world.

Our centre is one of the participating centres for umbilical cord blood transplant in Eurocord Registry. The Singapore Public Cord Blood Bank is sited in KKH.