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Adj Asst Prof Wong Chui Mae

FRCPCH (UK), FAMS (Spore), PhD (UK), MRCPCH (UK), MRCP (UK), MBBS (UK), Bachelor of Medical Sciences with First Class Honours (UK)

Senior Consultant

KK Women's and Children's Hospital KK Women's and Children's Hospital

Specialty: Paediatrics

Clinical Appointments

Senior Consultant

Child Development

Senior Consultant

Neonatology

Academic Appointments

Clinical Assistant Professor, Duke-NUS Medical School

Clinical Senior Lecturer, NUS Yong Loo Lin School of Medicine

Adjunct Assistant Professor, Lee Kong Chian Medical School

About

Dr Wong Chui Mae is a Senior Consultant Paediatrician in the Departments of Child Development and Neonatology. She joined the KK Women’s and Children’s Hospital in 2011, having worked in Paediatrics in the UK for 15 years before that. She was accredited as a Specialist in Paediatric Medicine and Neonatology in 2010 by the General Medical Council, UK. Dr Wong is certified in Bayley and Griffiths Developmental Assessments, as well as the ADOS and ADI-R diagnostic tools for autism.

Dr Wong holds a PhD from the University of Edinburgh and has sub-specialty research interests in autism spectrum disorder and the effect of screen time and sleep on children. She led the Autism Track Services at KK Hospital from 2013-2025 and has completed various research projects on Autism. She co-chaired the Academy of Medicine, Singapore’s 2023 Clinical Practice Guidelines on Autism in Children and is a member of the Maternal and Child Health Research Institute. Dr Wong has also served on the SingHealth Centralised Institutional Review Board since 2014.

Dr Wong is a member of the International Society for Autism Research (INSAR), Australasian Society for Autism Research (ASFAR), the Academy of Medicine, Singapore (College of Paediatrics and Child Health, Singapore; Section of Developmental and Behavioural Paediatrics), the Singapore Paediatric Society, the Royal College of Paediatrics and Child Health (UK), and the Royal College of Physicians of Edinburgh (UK).

Education and Training

  • FRCPCH, Royal College of Paediatrics and Child Health, UK , 2016
  • FAMS, Singapore 2013
  • PhD, University of Edinburgh, UK 2006
  • MRCPCH, Royal College of Paediatrics and Child Health, UK 2000
  • MRCP, Royal College of Physicians, UK 1999
  • MBBS, University of Nottingham, UK 1996
  • Bachelor of Medical Sciences with First Class Honours, University of Nottingham, UK 1994

Professional Appointments and Committee Memberships

  • Senior Consultant Paediatrician, KK Women’s and Children’s Hospital
  • Honorary Secretary, Section of Developmental and Behavioural Paediatrics, CPCHS, AMS
  • Co-chair, 2023 Clinical Practice Guidelines on Autism in Children and Adolescents, CPCHS, AMS
  • Executive committee member, Singapore Paediatric Society
  • Board Member, SingHealth Centralised Institutional Review Board
  • Committee Member, Maternal and Child Health Research Institute
  • Clinical Assistant Professor, Signature Research Programme in Neuroscience & Behavioural Disorders (NBD), Office of Research, Duke-NUS Medical School

Awards

 

  • 2026 Singapore Health Quality Service Gold Award, SingHealth Duke-NUS
  • 2025 Singapore Health Quality Service Silver Award, SingHealth Duke-NUS
  • 2024 Service from the Heart Award Jan to Dec 2023, KKH
  • 2024 SingHealth CIRB 10 Year Long Service Award
  • 2023 Covid-19 Resilience Medal, MOHH
  • 2022 Singapore Health Quality Service Gold Award, SingHealth Duke-NUS
  • 2022 SingHealth/KKH 10 Year Long Service Award
  • 2019 Singapore Health Quality Service Gold Award, SingHealth Duke-NUS
  • 2017 NUS-Yong Loo Lin School of Medicine Teacher’s Day Award
  • 2016 Singapore Health Quality Service Star Award, SingHealth Duke-NUS
  • 2016 Service from the Heart Award Jan to Dec 2015, KKH
  • 2015 Singapore Health Quality Service Gold Award, SingHealth Duke-NUS
  • 2013 Service From The Heart Award Jan-June 2013, KKH
  • 2013/2014 NUS-Yong Loo Lin School of Medicine Wong Hock Boon-SMA Charity Fund Best Mentor Award
  • 2013 Singapore Health Quality Service Silver Award, SingHealth Duke-NUS

 

 

 

Research Interests

  • Folinic Acid as a Treatment for Autism Spectrum Disorder in Children (FOLIN-A Trial)
  • Adaptive Behaviour and Independent LIving in Teenage Youths on the autism spectrum (the ABILITY Study)
  • Probing and Machine Learning of Multi-modal Neurophysiology-Behavioural Activities in Early Childhood of Developing Autism Spectrum Disorders (NeuroBeA)
  • MultIMOdal Surveillance for Autism (MIMOSA) Project – A Tool for Screening and Assessing Response to Intervention
  • Outcomes of Children with Autism Spectrum Disorder
  • Comorbidity of autism and ADHD symptomatology in pre-school children in Singapore

Research Trials

  • 2025 Folinic Acid as a Treatment for Autism Spectrum Disorder (ASD) in Children: A Double-blind Randomised Placebo-controlled Trial with Open Label Extension (FOLIN-A Trial)
  • 2023 Folinic Acid as a Treatment for Autism Spectrum Disorder in Children: An Open Label Pilot Study (FOLIN-P)
  • 2019 Autologous Umbilical Cord Blood Reinfusion for the Treatment of Autism – Safety and Efficacy

Publications

  • Wong CM, Koh HC. Brief Report: Investigating the Implications of Applying the New DSM-5 Criteria for Diagnosing Autism Spectrum Disorder in a Preschool Population in Singapore. J Autism Dev Disord. 2016;46(9):3177-3182.
  • Wong CM, Koh HC, Agarwal P, Daniel LM. Diagnostic patterns and predictors of cognitive outcomes in autistic children in Singapore. Ann Acad Med Singap. 2025 Jul; 54(7):396-409.Zambri NM, Koh HC, Daniel LM, Wong CM. Identifying the Best Discriminating Items for Three Autism Screening Methods in a High-Likelihood Sibling Population. J Autism Dev Disord. 2025 Jul 26.
  • Kim S, Zhang X, Sawant S, Poon KK, Khoo PC, Wong CM, Daniel LM, Law EC, Lee E, Leong V. Challenges and opportunities for early childhood intervention services in Singapore: addressing user satisfaction. Front Public Health. 2025 Jul 1;13:1566167.
  • Yeleswarapu SP, Wong CM, Chan YH, Daniel LM, Jiawen OX, Ng DCC, Guo X, Siriamornsarp R, Agarwal PK. Outcomes from an enhanced developmental screening programme in Singapore. Early Hum Dev. 2025 Mar;202:106220.
  • Wong CM, Tan CS, Koh HC, Gan X, Hie SL, Saffari SE, Yeo JG, Lam JCM. Folinic acid as a treatment for autism in children: A within-subjects open-label study on safety and efficacy. Int J Dev Neurosci. 2025 Feb;85(1):e10402.
  • Wong CM, Mohd Zambri N, Fan HH, Lau LHS, Daniel LM, Koh HC. A Direct Comparison of Three Screening Methods for Autism Spectrum Disorder in a High-Likelihood Sibling Population. J Autism Dev Disord. 2025 Apr;55(4):1274-1285.
  • Teo T, Koh HC, Mohd Zambri N, Zaccario ML, Sossin KM, Wong CM. Ethnic Group Differences in the Timing of Autism Diagnosis, Intellectual Disability, and Educational Placement of Autistic Children in Singapore. J Racial Ethn Health Disparities. 2025;12(2):1240-1250.
  • Wong CM, Tan CS, Riard N, Padmini YS, Daniel LM, Prasath A, Tan AM, Tan TC, Sultana R, Lam JCM. Autologous umbilical cord blood infusion for the treatment of autism in young children: A within-subjects open label study on safety (assessed via caregiver report) and efficacy. Autism Res. 2024 Aug;17(8):1721-1734.
  • Wong CM, Aljunied M, Chan DKL, Cheong JMY, Chew B, Chin CH, Choo SHT, Chua AHL, Foo MTS, Goh TJ, Khader M, Khoo SKM, Koh HC, Lian WB, Lim HH, Poon KK, Sim ZL, Sung M, Tan PC, Yong S, Zhang G, Aishworiya R. 2023 clinical practice guidelines on autism spectrum disorder in children and adolescents in Singapore. Ann Acad Med Singap. 2024 Apr 29;53(4):541-552.
  • Loo BKG, Sirisena D, Müller-Riemenschneider F, Chia MYH, Tan B, Tan NC, Teoh OH, Lim EJK, Zainuddin MA, Gao JS, Chan PC, Tan TSZ, Visruthan NK, Rajadurai VS, Chia MS, Ahmad Hatib NAB, Cai S, Ong JL, Lo JCY, Chong MF, Lee LY, Chew ECS, Siriamornsarp R, Lee M, Sim A, Wong CM, Sherwood SA, Toh SH, Quah PL, Ng KC, Tan KH, Lee YS. Consensus statement on Singapore integrated 24-hour activity guide for early childhood. Ann Acad Med Singap. 2023 Jun 27;52(6):310-320.
  • Madayi A, Padmini YS, Wong CM. An Audit on the Impact of Singapore’s COVID-19 Circuit Breaker Measures on Children with Developmental Delays and Their Families. Asia Pac J Paediatr Child Health 5:27-35, November 2022
  • Suhumaran S, Leong GKY, Wong CM. Knowledge and Awareness of Autism Spectrum Disorder among Paediatricians and Primary Healthcare Professionals in Singapore. Asia Pac J Paediatr Child Health 4:29-38, September 2021
  • Raturi S, Li FX, Wong CM. Recognition and management of bladder bowel dysfunction in children with autism spectrum disorder. BMJ Case Rep. 2021 Jun 1;14(6):e242646.
  • Suhumaran S, Yeleswarapu SP, Daniel LM, Wong CM. Congenital blindness and autism spectrum disorder (ASD): diagnostic challenges and intervention options. BMJ Case Rep. 2020 Feb 11;13(2):e232981.
  • Lin J, Magiati I, Chiong SHR, Singhal S, Riard N, Ng IH, Muller-Riemenschneider F, Wong CM. The Relationship Among Screen Use, Sleep, and Emotional/Behavioral Difficulties in Preschool Children with Neurodevelopmental Disorders. J Dev Behav Pediatr. 2019;40(7):519-529.
  • Tsang LPM, How CH, Yeleswarapu SP, Wong CM. Autism spectrum disorder: early identification and management in primary care. Singapore Med J. 2019 Jul;60(7):324-328.
  • Koh HC, Ang SK, Kwok J, Tang HN, Wong CM, Daniel LM, Goh W. The Utility of Developmental Checklists in Parent-held Health Records in Singapore. J Dev Behav Pediatr. 2016;37(8):647-656.
  • Wong CM, Singhal S. INDT-ASD: an autism diagnostic tool for Indian children. Developmental pediatrician's perspective. Indian Pediatr. 2014 May;51(5):355-6.