Our Research

The Principle Investigator (PI):

Professor Leung Wing Hang
Director, KKH Children’s Blood and Cancer Center 
Senior Consultant, Haematology/Oncology Service, Division of Medicine, KK Women’ and Children’s Hospital

Professor Leung is the Director of the Children's Blood and Cancer Centre and a Senior Consultant at KK Women's and Children's Hospital, part of SingHealth. He also serves as a Professor at Duke-NUS Medical School.

Previously, Professor Leung was a faculty member at Johns Hopkins University, where he held the position of Chair of Bone Marrow Transplantation and Cellular Therapy at St. Jude Children's Research Hospital. He also served as the Chair of the Department of Paediatrics at the University of Hong Kong. He was honored with the title of Distinguished Professor and Chair of the SingHealth Duke-NUS Tan Cheng Lim – CCF Professorship in Paediatric Oncology.

Throughout his career, Professor Leung has held several significant appointments, including Lead for SingHealth Transplant Research, Director of the Paediatric Bone Marrow Transplantation and Cellular Therapy Centre, and Director of Research at the SingHealth Duke-NUS Transplant Centre.

His research interests focus on the biology of human natural killer cells and T-memory cells, with a particular emphasis on their clinical applications in the treatment of cancer, blood disorders, immune system conditions, and infectious diseases.

About the laboratory:

The Teo Sok Yong and Goh Cheng Liang Childhood Cancer Laboratory @ Academia conducts basic science investigations and generates preclinical and correlative research which will be of immediate translational use in the clinics. Our laboratory is situated in the Discovery Tower at Academia, which houses SingHealth’s research laboratories and experimental animal facilities, within the vicinity of Duke-NUS Medical School. The vision is for a seamless circuit from innovation and discovery to animal in vivo studies and finally to the bedside, with robust correlative platforms and generating more areas of research. We aim to increase collaborations and exchanges with other centres to advance transplantation and cellular therapy in Singapore and beyond.

Some of the Programme's collaborations:

• External: NCCS Cancer Discovery Hub and NCCS Laboratory of Cell Therapy and Cancer Vaccines, Health Sciences Authority, Cell Therapy Facility, NUH Stem Cell Laboratory
• Internal: Brain and Solid Tumour Programme

Laboratory Journals:

W Leung, TG Soh, YC Linn, JGH Low, JS Loh, M Chan, WJ Chng, LP Koh, ML Poon, KP Ng, CH Kuik, TT Tan, LK Tan, MS Seng. Rapid production of clinical-grade SARS CoV-2 specific T cells. Adv Cell Gene Ther. 2020 Oct; 3(4):e101.
DOI:10.1002/acg2.101 PMID 32838213

For more information, visit our laboratory webpage via this Link