Archer FUSIONPlex pan solid tumour v2 assay

HT0213

Synonym(s):
Specimen Requirement
10 unstained sections of tumour and a corresponding H&E-stained histological section, OR

1 paraffin block of tumour
Orderable as Urgent? No
Turn Around Time
The test is batched and performed every Monday. The test itself takes 5 working days to complete.
Testing Laboratory Location KKH
Laboratory Molecular Pathology
Contact Number 6394 1402
Day and Time Performed
Mon – Fri: 0800 hrs– 1700 hrs
Orderable on CPOE? No
Downtime Form

Molecular Pathology Test Request Form

Additional Information
Background:
A proportion of solid tumours including sarcomas have gene fusions. Identification of specific gene fusions are important for diagnosis and may provide prognostic and predictive information.

Purpose of test:
This test identifies the presence of a gene fusion involving any of the 129 listed genes known to be involved in gene fusions in solid tumours of various histological subtypes by next-generation sequencing-based anchored multiplex PCR (Archer FusionPlex). Prior knowledge of the fusion breakpoints and partner genes is not required, and the breakpoints and partner genes are idenotified through their sequences. Refer to test request form for gene list.

Caveats:
RNA integrity and concentration must meet assay requirements. Low tumour content (<50%) may result in an inaccurate result.

Proficiency testing:
College of American Pathologists proficiency testing programme.

Change History Notes

  • 07 Jul 2025 09:17 AM

    Update Additional Information

  • 18 Jun 2025 03:40 PM

    Update test name and downtime form

  • 12 Apr 2024 10:00 AM

    Update on Test name, specimen requirement, TAT, additional information and editorial edits.

  • 06 Oct 2022 12:00 AM

    Updated Additional Information.

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Last Updated - 07 Jul 2025