Test Code:
Synonym(s):
Ewing tumours form a histologically heterogeneous family belonging to the group of small round-cell tumours and derived from neural crests cells. Ewing’s sarcoma represents 5 to 15% of malignant bone and soft tissue tumours. About 90% of Ewing’s tumours show a t(11;22)(q24;q12); the translocation results in the fusion of the EWS gene with the transcription factor gene FLI1, leading to a hybrid transcript and an oncogenic chimeric protein. The Type 1 translocation has a different clinical prognosis than Type 2 translocation. Our real-time RT-PCR assay identifies both the FLI1t(11;22)(q24;q12) Type 1 and Type 2 translocations.
Expected Test Result:
{0}
{1}
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