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Prof Ivy Ng Swee Lian

Prof Ng Swee Lian Ivy


Senior Consultant

KK Women's and Children's Hospital

Specialty: Paediatric Genetics

Conditions Treated by this Doctor:
Genetic Syndromes, Prenatal and Genetic Counselling, Thalassaemia, Thalassaemia, Thalassaemia (Child).

Clinical Appointments

  • Group Chief Executive Officer SingHealthSingHealth
  • Senior Consultant, Med: Paediatrics SingHealth Duke-NUS Genomic Medicine Centre
  • Senior Consultant Genetics Service KK Women's and Children's HospitalKK Women's and Children's Hospital


Professor Ivy Ng has been the Group CEO of SingHealth since January 2012. Prior to her appointment as SingHealth’s GCEO, Prof Ng was the CEO of KK Woman’s and Children’s Hospital (KKH) from 2004 to 2012, and Deputy CEO of SingHealth from 2008 to 2012. She was KKH’s Chairman of the Medical Board from 2003 to 2004 and Head of the Hospital’s Department of Paediatric Medicine from 2002 to 2003.

A paediatric geneticist by training, Prof Ng is a practising clinician and serves as Senior Consultant in the Genetics Service, Department of Paediatric Medicine at KKH and Director of the National Thalassaemia Registry. Prof Ng’s research interests include thalassaemia (prevention, molecular variants, epidemiology), dysmorphology and mental retardation. She is known for her work in thalassemia, and has published extensively in the area of genetic counselling and thalassemia.

On the education front, Prof Ng plays an active role in the education of medical students and Residents in her capacities as Clinical Professor of Yong Loo Lin School of Medicine, NUS and Adjunct Professor of Duke-NUS.


  • Fellow, Royal College of Paediatrics and Child Health (London) – 2003
  • Fellow, Royal College of Physicians (Edinburgh) – 2001
  • Academy of Medicine, Roll of Specialists – Paediatrics – 1992
  • Fellow, Academy of Medicine, Singapore – 1992
  • Master of Medicine (Paediatrics) – 1987
  • Bachelor of Medicine and Bachelor of Surgery (Singapore) – 1982

Professional Appointments and Committee Memberships

Professional Appointments

  • Adjunct Professor, Duke-NUS Medical School Singapore
  • Clinical Professor, National University of Singapore
  • Member, Singapore Paediatric Society
  • Member, American Society of Human Genetics
  • Director, National Thalassaemia Registry, Ministry of Health
  • Member, College of Paediatric & Child Health, Academy of Medicine
  • Member, International Women’s Forum
  • Member, Asia Pacific Society of Human Genetics

Committee Work

  • Member, Foundation Fund Committee, SingHealth Fund Limited
  • Chairman, KKH Fund Committee, SingHealth Fund Limited
  • Board Member, Biomedical Research Council (BMRC), A*STAR
  • Member, Singapore Management University (SMU) Board of Trustees
  • Member, Duke-NUS Governing Board
  • Co-Chair, MOH Compensation Implementation Committee (CIC)
  • Member, National Medical Research Council (NMRC) Board
  • Chairman, Infrastructure Review Panel (IRP), NMRC
  • Member, NMRC Open Fund Large Collaboration Grant Review Panel (OF-LCGRP)


  • Her World – Woman of the Year 2012
  • Public Administration Medal (Gold) – 2011
  • 7th International Management Action Award – 2010
  • May Day Award – Medal of Commendation – 2009
  • Leading CEO Award 2008, Singapore Human Resource Institute - 2008

Research Interests

  • Molecular Genetics
  • 1.1 ß-Thalassaemia Mutations & Strategies in Screening
    1.2 DNA Profiling and its Application in Prenatal Diagnosis
    1.3 Trinucleotide Repeat Diseases
    1.4 Next Generation Sequencing
  • Dysmorphology


Referred Journals (International)
  • Down Syndrome in Diverse Populations
    Paul Kruszka, Antonio R. Porras, ISL Ng, Breana Cham Wen Min, Saumya S. Jamuar, et al.
    American Journal of Medical Genetics – Part A - January 2017
  • Incidentalome from Genomic Sequencing: A Barrier to Personalized Medicine?
    Saumya Shekhar Jamuar, Jyn Ling Kuan, Maggie Brett, Zenia Tiang, Wilson Lek Wen Tan, Jiin Ying Lim, Wendy Kein Meng Liew, Asif Javed, Woei Kang Liew, Hai Yang Law, Ee Shien Tan, Angeline Lai, ISL Ng, Yik Ying Teo, Byrappa, Venkatesh, Bruno Reversade, Ene Choo Tan, Roger Foo
    Accepted in EBioMedicine (2016),
  • Next-generation sequencing using a pre-designed gene panel for the molecular diagnosis of congenital disorders in pediatric patients
    Eileen C.P. Lim, Maggie Brett, Angeline H.M. Lai, Siew-Peng Lee, Ee-Shien Tan, Saumya S. Jamuar, ISL Ng and Ene-Choo Tan
    Human Genomics (2015) 9:33
  • Molecular Diagnosis of Congenital Genetic Disorders using the ICCG Gene Panel and Ion Torrent Sequencing
    Eileen CP Lim, Maggie Brett, Angeline HM Lai, Siew-Peng Lee, Ee-Shien Tan, Saumya S Jamuar, ISL Ng, Ene-Choo Tan
    Biomedical Central Medical Genomics Journal, 24 Apr 2015
  • An Additional Case of the Recurrent 15q24.1 Microdeletion Syndrome and Review of the Literature
    ISL Ng, WH Chin, ECP Lim, EC Tan
    Twin Research & Human Genetics 2011;14(4):333-9.
  • Massively Parallel Sequencing of Patients with Intellectual Disability, Congenital Anomalies and/or Autism Spectrum Disorders with a Targeted Gene Panel
    Maggie Brett, John McPherson, Zhi Jiang Zang, Angeline Lai, Ee-Shien Tan, ISL Ng, Lai-Choo Ong, Breana Cham, Patrick Tan, Steve Rozen, Ene-Choo Tan
    PLOS One: PONE-D-13-41475R1; April 2014, Volume 9, Issue 4, e93409
  • De novo Trisomy 12p in Twin Girls with Different Levels of Mosaicism
    Eileen C.P. Lim, ISL Ng, Min-Hwee Yong, Hui-Yi Yon, Maggie S.Y. Brett, Ene-Choo Tan
    American Journal of Medical Genetics: Part A, 12-0838.R1 , 2013
  • De Novo 3q22.1 q24 Deletion Associated with Multiple Congenital Anomalies, Growth Retardation and Intellectual Disability
    Maggie S. Brett, ISL Ng, Eileen CP Lim, Min Hwee Yong, Zhihui Li, Angeline Lai, Ene-Choo Tan
    Gene 517 (2013) 82-88
  • Partial Trisomy 3p and Partial Monosomy 11q Associated with Atrial Septal Defect, Cleft Palate and Developmental Delay: A Case Report
    EC Tan, E Lim, B Cham, L Knight, ISL Ng
    Cytogenetic and Genome Research 2011;134:319-24.
  • Use Of Deferiprone For Iron Chelation In Patients With Transfusion-Dependent Thalassaemia
    SS Jamuar, AHM Lai, AM Tan, MY Chan, ES Tan, ISL Ng
    Journal of Paediatrics & Child Health, Sept 2011 doi: 10.1111/j.1440-1754.2011.02031.x

Research Trials