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Clin Asst Prof Looi Wen Shen

Clin Asst Prof Looi Wen Shen

MBBS, FRCR (Clinical Oncology)


National Cancer Centre Singapore

Specialty: Radiation Oncology

Sub-specialties: Sarcoma/Skin, Uro-Oncology, Paediatric Oncology, Lymphoma, Sarcoma

Conditions Treated by this Doctor:
Lymphoma, Paediatric Cancer, Sarcoma, Skin Cancer, Urological Cancers.

Clinical Appointments

  • Consultant Division of Radiation Oncology National Cancer Centre SingaporeNational Cancer Centre Singapore
  • Visiting Consultant Paediatric Brain and Solid Tumour Programme KK Women's and Children's HospitalKK Women's and Children's Hospital

Academic Appointments

  • Clinical Assistant Prof at Duke-NUS Medical School


 Dr Looi Wen Shen is a Consultant radiation oncologist in the Department of Radiation Oncology at the National Cancer Centre, Singapore, and a Clinical Assistant Professor in Duke-NUS medical school. He is fellowship-trained, having completed a year-long fellowship in paediatric and adult proton therapy at the University of Florida Health Proton Therapy Institute. He specialises in caring for both adults and children, and has an interest in paediatric tumours, urologic tumours, sarcomas, and lymphomas.

After receiving his undergraduate medical degree from Yong Loo Lin School of Medicine, National University of Singapore, Dr Looi went on to complete his residency training in National Cancer Centre, Singapore before receiving specialist accreditation in radiation oncology by the Specialist Accreditation Board. He is an active cancer researcher and his research has been published in respected journals such as the International Journal of Radiation Oncology Biology and Physics, and Medical Physics, Pediatric Blood and Cancer, and the Archives of Disease in Childhood. Through his research, he endeavours to decrease the acute and late side effects of radiation in children and adults, and improve their quality of life.


  • 2020 – 2021 Postdoctoral Fellowship
    Paediatric and Adult Proton Fellowship University of Florida Health Proton Therapy Institute
  • 2017  Postgraduate Diploma
    Fellow of the Royal College of Radiology (UK) Clinical Oncology
  • 2013 – 2017 Residency – Radiation Oncology
    National Cancer Centre, Singapore
  • 2003 – 2008  Bachelor of Medicine, Bachelor of Surgery (M.B.B.S.)
     Yong Loo Lin, School of Medicine, National University of Singapore


  • 2020  Standard Certificate for United States Medical Licencing Examination
    Education Commission for Foreign Medical Graduates (ECFMG)
  • 2019  Essential Skills in Medical Education Certificate (ESME)
     Association for Medical Education in Europe (AMEE)
  • 2017 Radiation Oncology
     Specialist Accreditation Board, Singapore
  • 2008 Medical Practicing Certificate
     Singapore Medical Council

Professional Appointments and Committee Memberships

Past and Present Appointments

  • 2021 –  Clinical Assistant Professor, Duke-NUS
  • 2021 –  Clinical Instructor, Lee Kong Chian, School of Medicine
  • 2020 – 2021  Postdoctoral Fellow, University of Florida, Proton Therapy Institute
  • 2019 –  Visiting Consultant, Hematology/Oncology Service, KKH, Singapore.
  • 2019 – 2021 Clinical Instructor at Duke-NUS Medical School
  • 2017 –  Consultant, Radiation Oncology, National Cancer Centre, Singapore

 Professional Licensure

  • 2008  Practicing Certificate
      Singapore Medical Council

  • 2017  Radiation Oncology Specialty Certificate
      Specialist Accreditation Board of Singapore

  • 2020 - 2022 Registration for Resident / House Physician
    Florida Board of Medicine

Professional Memberships

  • 2018 – 2019 Singapore Radiological Society, Executive Committee Member
  • 2017 –  Royal College of Radiology (Clinical Oncology), Fellow (FRCR)
  • 2017 – 2021 Academy of Medicine, Fellow (FAMS)
  • 2008 – 2014 Singapore Medical Association, Member
  • 2021 –  Children’s Oncology Group, International Associate Member
  • 2021 –  VIVA Asia Brain and Solid Tumour Working Group Member
  • 2019 –  Paediatric Radiation Oncology Society, Member
  • 2020 –  American Society for Radiation Oncology


  • Health Manpower Development Program (HMDP) award 2019
  • SAF resuscitation distinction award 2016

Research Interests


1. Looi WS, Bradley JA, Liang XY, Shaw CM, Leyngold M, Mailhot Vega RB, Brooks ED, Rutenberg MS, Spiguel LR, Giap F, Mendenhall NP. Hyperfractionated-Accelerated Reirradiation with Proton Therapy for Radiation-Associated Breast Angiosarcoma. Int J Part Ther. 2022.
2. Koh KN, Wong RX, Lee DE, Han JW, Byun HK, Yoon HI, Kim DS, Lyu CJ, Kang HJ, Hong KT, Lee JH, Kim IH, Phi JH, Kim SK, Wong TT, Lee HL, Lai IC, Kang YM, Ra YS, Ahn SD, Im HJ, Looi WS, Low SYY, Tan EEK, Park HJ, Shin SH, Fuji H, Suh CO, Chen YW, Kim JY. Outcomes of intracranial germinoma-a retrospective multinational Asian study on effect of clinical presentation and differential treatment strategies. Neuro Oncol. 2021 Dec 22:noab295. doi: 10.1093/neuonc/noab295. Epub ahead of print. PMID: 34935949.
3. Looi WS, Indelicato DJ, Rutenberg MS. The Role of Radiation Therapy for Symptomatic Desmoid Tumors. Curr Treat Options Oncol. 2021 Mar 1;22(4):34. doi: 10.1007/s11864-021-00831-6. PMID: 33649873.
4. Bte Syed Sulaiman, N.; Kuick, C.H.; Chang, K.T.E.; Wan, K.R.; Looi, W.S.; Low, D.C.Y.; Seow, W.T.; Low, S.Y.Y. Cytokines in Pediatric Pilocytic Astrocytomas: A Clinico-Pathological Study. NeuroSci 2021, 2, 95-108.
5. Indelicato DJ, Bates JE, Mailhot Vega RB, Rotondo RL, Hoppe BS, Morris CG, Looi WS, Sandler ES, Aldana PR, Bradley JA. Second tumor risk in children treated with proton therapy. Pediatr Blood Cancer. 2021 Feb 9:e28941. doi: 10.1002/pbc.28941. Epub ahead of print. PMID: 33565257.
6. Indelicato DJ, Rotondo RL, Mailhot Vega RB, Holtzman AL, Looi WS, Morris CG, Sandler ES, Aldana PR, Bradley JA. Local Control After Proton Therapy for Pediatric Chordoma. Int J Radiat Oncol Biol Phys. 2020 Nov 27:S0360-3016(20)34591-0. doi: 10.1016/j.ijrobp.2020.11.051. Epub ahead of print. PMID: 33253819.
7. Looi WS, Indelicato DJ, Mailhot Vega RB, Morris CG, Sandler E, Aldana PR, Bradley JA. Outcomes following limited-volume proton therapy for multifocal spinal myxopapillary ependymoma. Pediatr Blood Cancer. 2021 Mar;68(3):e28820. doi: 10.1002/pbc.28820. Epub 2020 Nov 23. PMID: 33226179.
8. Low SYY, Bte Syed Sulaiman N, Tan EEK, Ng LP, Kuick CH, Chang KTE, Tang PH, Wong RX, Looi WS, Low DCY, Seow WT. Cerebrospinal fluid cytokines in metastatic group 3 and 4 medulloblastoma. BMC Cancer. 2020 Jun 15;20(1):554. doi: 10.1186/s12885-020-07048-0. PMID: 32539808; PMCID: PMC7296667.
9. Pang EPP, Knight K, Park SY, Lian W, Master Z, Baird M, Chan JWX, Wang MLC, Tan TWK, Chua MLK, Chua ET, Looi WS, Nei WL, Tuan JKL. Duration-dependent margins for prostate radiotherapy-a practical motion mitigation strategy. Strahlenther Onkol. 2020 Jul;196(7):657-663. doi: 10.1007/s00066-019-01558-y. Epub 2020 Jan 13. PMID: 31932995.
10. Looi WS, Goh SH, Tan CJ, Yeoh KW, Seng MS. Adolescent with facial swelling. Arch Dis Child Educ Pract Ed. 2019 Oct 22:edpract-2019-317654. doi: 10.1136/archdischild-2019-317654. Epub ahead of print. PMID: 31641021.
11. Looi WS, Low DCY, Low SYY, Goh SH. Neonatal orbital swelling due to intracranial teratoma. Arch Dis Child Fetal Neonatal Ed. 2019 Jul;104(4):F365. doi: 10.1136/archdischild-2018-316337. Epub 2018 Dec 14. PMID: 30552092.

Research Trials