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Clin Assoc Prof Nadarajah Sadhana

Fellow of the Academy of Medicine, Member of the Royal College Of O&G, MBBS

Head ＆ Senior Consultant

KK Women's and Children's Hospital

Specialty: Obstetrics ＆ Gynaecology, Menopause, Endometriosis, Reproductive Medicine

Sub-specialties: Assisted Reproductive Program, Infertility, Polycystic Ovarian Syndrome, Endocrinology, Adolescent Gynaecology, Reproductive Surgery

Conditions Treated by this Doctor:
Adolescent Gynaecology, Clomid, Donor Insemination Programme, Endometriosis, Endometriosis and Ovarian Cysts, Fallopian Tubal Recanalisation (FTR), Fibroids, Fibroids of the uterus, General Obstetrics ＆ Gynaecology, Infertility, In-Vitro Fertilisation (IVF)/Intra-Cytoplasmic Sperm (ICSI), Menstrual Problems/Irregular Menses, Ovarian Cysts, Superovulation and Intrauterine Insemination.

Clinical Appointments

Head ＆ Senior Consultant Reproductive Medicine KK Women's and Children's Hospital
Senior Consultant KKIVF (In-vitro Fertilisation) Centre KK Women's and Children's Hospital
Head, Adolescent Gynae Unit Reproductive Medicine KK Women's and Children's Hospital

Profile

Clin Assoc Prof Sadhana Nadarajah is a Senior Consultant in Department of Reproductive Medicine in KK Women’s & Children’s Hospital (KKH). She is also the Head of Adolescent Gynaecology Unit in KKH.
She received her Bachelor of Medicine and Bachelor of Surgery (MBBS) from the National University of Singapore in 1990 and obtained her post graduate training in OBGYN in 1996. She trained in Adolescent Gynaecoloy in Queen Charlotte’s Hospital in London and has been practicing IVF for the last 18 years.
Apart from clinical work, Dr Sadhana is also very involved in teaching the undergraduate and postgraduate medical students.

Education

1999 to date Fellow of the Academy of Medicine
1996 Member of the Royal College Of O&G
1990 MBBS

Professional Appointments and Committee Memberships

Clinical Associate Professor, Duke-NUS Medical School - 2022 to Present
Adjunct Assistant Professor, Duke-NUS Medical School - 2009 to 2021
Medical Undergraduate Examiner, Yong Loo Lin School of Medicine - 2004 to present
Clinical Tutor - 1996
Senior Consultant, Department of Reproductive Medicine - Present
Head, Adolescent Gynae Unit - Present
Examiner, Medical Undergraduate Examiner YLL - Present
Member, O&G Society - Present
MOH appointment, to Assisted Reproduction Services Working Committee - Present
Senior Consultant, MOH, Regulatory Policy & Legislation Division - 2017
MOH appointment, to Pro-Tem Subcommittee for Exemption from Commercial Trading Clauses (Therapy) - 2017
Advisory Committee on Biobanking to MOH - 2014
Non-executive director to Babes Pregnancy Crisis Support Limited - 2013
Co Chairman Gynaecological Surgery section of KK Medical procedures Accreditation Committee - 2010
Chairperson of Adolescent Gynaecology/sexual sub-health committee - 2010
Organising Committee 6th Singapore Congress of O&G - 2007
Singapore Advisory Work-Group on HPV Vaccine - 2006
HPB Workgroup for Adolescent Health Promotion Blueprint - 2006
National Adolescent Health Committee - 2006
Member, British Society For Paediatric & Adolescent Gynaecology - 2001
Member, North American Society For Pediatric &Adolescent Gynecology - 2000 to 2004
Visiting, Consultant to School Health Services - 1999 to 2006

Awards

Singapore Health Quality Service Award (Star), Apr 2012 - Mar 2013
Singapore Health Quality Service Award (Silver), Apr 2010 - Mar 2011
Excellent Service Star Award, 2010
Service from the heart award, 2009
Service from the heart award, 2008
Excellent Service Silver Award, 2007
Excellent Service Silver Award, 2006
Excellent Service Silver Award, 2004

Research Interests

Publications

The Asian Textbook of Emergency Medicine Paediatric section
(Author for chapter on Paediatric emergencies Gynaecological Disorders
Teenage abortions at KKH, XVIII FGO World Congress 2006
Extended Culture and Blastocyst transfer of cryopreserved D2 - D3 embryos; FSA Meeting 2004
Uterovaginal anomalies in KK Hospital – our experience: SingHealth ASM 2004
Profile of Teenagers Seeking an Abortion; 1st Singapore Malaysia Conference in O&G 2003
Laparoscopic Oopharectomy in testicular fermising syndrome; North American Society of Pediatric & Adolescent Gynaecology Annual meeting 2002
Uterovaginal anomalies in KK Hospital – our experience: SingHealth ASM 2004
Complications in Adolescent pregnancies FIGIJ meeting 1999

Research Trials

To study the influence of pharmacogenomics factors on pharmacokinetics and pharmacodynamics of clomiphene in Asian normogonadotrophic anovulatory patients. SingHealth Foundation Grant, $150,000, Co-I (PI - Balram Chowbay), 2014 - 2016
Analysis of reproductive outcomes in in-vitro fertilisation (IVF). PI, 2014
Analysis of reproductive outcomes in in-vitro fertilisation (IVF). PI, 2014
Ovulation Induction with Letrozole versus Clomiphene Citrate in Asian women with PCOS: A prospective randomised controlled trial. Co-I (PI - Matthew), 2013 - 2015
Serum LH of women after starting GnRH antagonist in IVF stimulation cycles: who are at risk of profound suppression of endogenous LH production and how is treatment outcome affected? SingHealth Duke-NUS OBGYN (ACP) Grant Award (awarded 22/3/2013), $10,000, Co-I (PI - Steven), 2013 - 2014
Development of complementary diagnostic technology for embryo discrimination. Co-I (PI - HH Tan), 2013 - 2014
Human embryo cryopreservation: one-step slow freezing does it all? Co-I (PI - Chong Yee Shen), 2013
Use of GnRH antagonist pre-treatment for IVF/ICSI antagonist cycles scheduling. Co-I (PI - Veronique), 2013
"Rescue Technique"- the use of overnight matured oocytes to increase pregnancy potential. Co-I (PI - Lee Joo Mong), 2013
Fresh embryo transfer - does the days really matter? Co-I (PI - Farhana M Rafik), 2013
Comparison of outcome of fresh embryo transfer using sperm retrieved by MESA, TESE & TESA. Co-I (PI - Matthew), 2013
Validation of ovarian tissue cryopreservation for fertility preservation. Co-I (PI - Jessie), 2013 - 2015
Polycystic ovarian syndrome in Singapore: Norms for hyperandrognemia and metabolic syndrome. Co-I (PI - Yong Eu Leong), 2013
Knowledge, attitudes and perception of oocyte donation of women in Singapore. Co-I (PI - Jerry), 2013
GnRH agonist trigger and OHSS: Relook at 'freeze all strategy'. Co-I (PI - HH Tan), 2013
Significance of Progesterone level on Day 8 post embryo transfer during Long down regulation ART cycles. Co-I (PI - Sau Po Yi, Matthew Lau), 2012 - 2014
Serum Progesterone levels and pregnancy in controlled ovarian stimulation cycles using antagonist protocol for in vitro fertilization. Co-I (Qi Maili, Matthew Lau), 2012 - 2014
Predictors and outcomes of surgical sperm retrieval. Co-I (PI - TY Tan), 2012 - 2013
Patients attitudes towards single embryo transfer and multiple pregnancy & review of multiple pregnancy rates after elective single embryo transfer. Co-I (PI - TY Tan), 2012 - 2013
Lifestyle behaviour in women undergoing In Vitro Fertilisation in Singapore: A cross sectional survey. Co-I (PI - Matthew), 2012
Social Oocyte Freezing: A survey amongst Singapore female medical students. Co-I (PI - Andy Tan, Shu Qi), 2012
Dehydroepiandrosterone (DHEA) treatment for poor responders in IVF patients: A prospective randomised controlled trial. Singhealth Foundation Grant - SHF/CTG034/2010 - Co-I (PI - Veronique) $199,000, 2011 - 2014
A Clinic based project on improving outcomes in unmarried teen pregnancies. PI, 2009 to 2011
A prospective randomized trial comparing use of vaginal utrogestan and intramuscular progesterone for luteal phase support following intracytoplasmic sperm injection. PharMed Project Based Research Grant - Co-I (PI - Kelly Loi) $12,900, 2007 - 2011
A Qualitative Analysis and Survey of the Knowledge, Attitudes and Sexual Health Behaviours of Pregnant Adolescents. Co-I (PI - Janice), Pending
What is the best way to achieve intra-ovarian haemostasis after cystectomy? A comparison between Tisseel, FloSeal and Bipolar diathermy with regards to their impact on ovarian reserve. Co-I (PI - Janice), Pending