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Dr Yan Zhiyan

Dr Yan Zhiyan

MBBS, MRCS, FRCS, MMed (Surgery), FRCS (Gen Surgery), FAMS (Surgery)

Senior Consultant

KK Women's and Children's Hospital

Specialty: Breast Surgery

Clinical Interest: Oncoplastic Breast Surgery

Conditions Treated by this Doctor:
Atypical Hyperplasia, Breast Cancer, Breast Cancer - Early Detection and Screening, Duct Ectasia, Fibrocystic Change, Intraductal Papillomas, Malignant and Benign Breast Conditions, Mastitis, Phyllodes Tumour.

Clinical Appointments

  • Senior Consultant KK Breast Centre KK Women's and Children's HospitalKK Women's and Children's Hospital
  • Senior Consultant SingHealth Duke-NUS Breast Centre
  • Clinical Assistant Professor, Duke-NUS Medical School
  • Clinical Lecturer, Yong Loo Lin School of Medicine


Dr Yan is a senior consultant oncoplastic breast surgeon at the Breast Centre, KK Women’s and Children’s Hospital and Clinical Assistant Professor with Duke-NUS Medical school. She was awarded the Ministry of Health Human Manpower Development Programme (HMDP) where she completed further subspecialty training in the field of oncoplastic breast surgery at the world renowned cancer institute Royal Marsden Hospital in London. Her current practice covers all benign breast conditions, diagnosis and management of breast cancer.

Dr Yan believes breast cancer care should be individualized and a good aesthetic outcome is as important as a good oncological outcome. She firmly believes in the importance of public education for early detection of cancer and speaks regularly in public forums in both English and Mandarin. Dr Yan’s research interest include the safe de-escalation of breast and axilla treatment and phyllodes tumours of the breast. In recognition of her dedication to the care of her patients she has been awarded multiple service awards. She is actively involved in the education of doctors and medical students and mentors both international and local doctors and students.


  • Fellow of the Royal College of Surgeons (Edinburgh)
  • Master of Medicine Surgery (Singapore)
  • Member of the Royal College of Surgeons (Edinburgh)
  • Bachelor of Medicine and Bachelor of Surgery (Distinction) St Barts and the Royal London School of Medicine and Dentistry. University of London

Professional Appointments and Committee Memberships

  • Clinical Assistant Professor, DUKE-NUS Medical School
  • Clinical Lecturer, Yong Loo Lin School of Medicine, National University Singapore
  • Member, Patient Experience Council
  • Member, Association of Breast Surgery
  • Fellow, Academy of Medicine Singapore
  • Fellow, Royal College of Surgeons Edinburgh


  • 2023 Singapore Health Quality Service Award (Star)
  • 2022 Service from the Heart Award
  • 2021 Singapore Health Quality Service Award (Gold)
  • 2020 Singapore Health Quality Service Award (Star)
  • 2019 SingHealth Health Manpower Development Plan (HMDP) in Advance Oncoplastic Breast Surgery at Royal Marsden Hospital
  • 2018 KK Women’s and Children’s Hospital Long Service Award (10years)
  • SingHealth Long Service Award (10 years)
  • 2019 Singapore Health Quality Service Award (Gold)
  • 2018 Singapore Health Quality Service Award (Silver
  • 2017 Service from the Heart Award

Research Interests


  • Axillary management of breast cancer patients with isolated chest wall recurrence after mastectomy, Ann Translational Medicine March 2023 11(6):240:d01.
    Lim GH, Alcantara V, Ng RP, Htein Min, QT Tan, SH Lim, Yan ZY
  • Patterns of breast care second recurrences in patients after mastectomy. Breast Cancer Research and Treatment 196(1) October 2022.
    Geok Hoon Lim, Veronica Alcantara, Swee Ho Lim, Yan ZY, QT Tan
  • Determining the benefit of neoadjuvant chemotherapy in reduction of axillary dissection rates in Z0011 trial cohort with high nodal burden. Gland Surg. 2022 May;11(5):788-794. doi: 10.21037/gs-22-7. PMID: 35694092; PMCID: PMC9177288.
    Yan ZY, Wong A, Ng RP, Lee YS, Lim MEA, Leong LCH, Allen J, Lim GH
  • Overlap of high-risk individuals predicted by family history, and genetic and non-genetic breast cancer risk prediction models: implications for risk stratification. BMC Med. 2022 Apr 26;20(1):150. doi: 10.1186/s12916-022-02334-z. PMID: 35468796; PMCID: PMC9040206.
    Ho PJ, Ho WK, Khng AJ, Yeoh YS, Tan BK, Tan EY, Lim GH, Tan SM, Tan VKM, Yip CH, Mohd-Taib NA, Wong FY, Lim EH, Ngeow J, Chay WY, Leong LCH, Yong WS, Seah CM, Tang SW, Ng CWQ, Yan ZY, Lee JA, Rahmat K, Islam T, Hassan T, Tai MC, Khor CC, Yuan JM, Koh WP, Sim X, Dunning AM, Bolla MK, Antoniou AC, Teo SH, Li J, Hartman M
  • Primary Eccrine Porocarcinoma of the Breast: A case Report and Review of the literature. Case reports in Oncological Medicine May 2022
    YX Li, Mihir Gudi, Yan ZY.
  • Aesthetic Breast Surgert: putting in context- a narrative review. Sept 21 Gland Surgery
    PG Roy, Yan ZY, Shashank Nigam, Kavish Maheshwari.
  • The Singapore Breast Cancer Cohort (SGBCC), a multi-center breast cancer cohort for evaluation of phenotypic risk factors and genetic markers. PLoS One. 2021 Apr 26;16(4):e0250102.
    Ho PJ, Yeoh YS, Miao H, Lim SH, Tan EY, Tan BKT, Tan VKM, Tan SM, Yong WS, Wong FY, Madhukumar P, Chan CW, Iau PTC, Lee SC, Putti T, Buhari SA, Lee JY, Lim GH, Woo E, Yan ZY, Chan PMY, Chen JJC, Lu SQ, Dent R, Lee WP, Mok CW, Seah JCM, Sim X, van Dam RM, Chia KS, Li J, Hartman M. Cohort profile
  • Association of initial number of sonographically abnormal nodes with nodal pathological response and its implication. Clinical imaging 78(2021)19-21
    Yan ZY, Adele Wong, Ruey Pyng Ng, Yien Sien Lee , Jorn Carson Allen, Lim Geok Hoon.
  • DNA methylation and breast cancer-associated variants
    Ho PJ, Dorajoo R,Ivankovic I, Ong SS, Khng AJ, Tan BK, Tan VKM, Lim SH, Tan EY, Tan SM, Tan QT, Yan ZY, Ngeow J, Sim Y, Chan P, Chuan CW, Tang SW, Hartman M, Li J
  • Preoperative radiological and histological features predict phyllodes tumour grade. The Breast Journal Volume 6 Issue 10 16 October 2020
    Yan ZY, Mihir Gudi,Seyed Ehsan Saffari, SH Lim, SY Teo, MY Leong, YS Lee, LC Lau, Thida Win, PH Tan.
  • The impact of radiotherapy and histological risk factors on outcomes in malignant phyllodes tumours.Clinical Breast Cancer 2020 May 13. Epub 2020 May 13.
    RX Wong,YS Koh,FY Wong,G Kusumawidjaja,WL Ng, Richard MC.Yeo, Mohamad Farid,Jason YongSheng Chan, Yan ZY, Mihir A.Gudi, PH Tan.
  • Would clipping and removal of all ultrasound abnormal metastatic lymph nodes predict nodal response in breast cancer patients with neoadjuvant chemotherapy Oncologist 2020 Jun 14. Epub 2020 Jun 14
    GH Lim Mihir G SY Teo, RP Ng, ZY Yan, YS Lee, JC Allen, LCH Leong
  • Diagnostic dilemma of micropapillary variant of mucinous breast cancer. BMJ Case Reports 2018:bcr-2018-225775 · August 2018.
    Lim GH, Yan ZY, Gudi Mihir
  • Lactational Adenoma: A diagnostic pitfull on fine needle aspiration cytology: International journal of clinoopathological correlation 2017DO1:10.4103/
    Wu BC, Yeo YC, Tay Ze, Yan ZY, Gudi Mihir
  • Discordant correlation of breast adenoid cystic carcinoma on imaging and pathology: A case report and literature review on surgical management. International Journal of Surgery Case reports. Volume 42, 2018, Pages 196-199
    Yan ZY, Leong MY, Lim GH
  • A Large Benign Phyllodes Tumour of the Breast: A Case Report and Literature review. International journal of Surgery case reports. Volume 39. 2017 P 192-195
    Yan ZY, Gudi M, Lim SH
  • Colonic diverticulitis in young Asians: a predominantly mild and right sided disease. ANZ journal of surgery 2013 June 25
    Tan KK, Wong JY, Yan ZY, Chong CS, Jody Z Liu, R Sim.
  • Surgical management of diaphragmatic rupture after blunt trauma-an institution experience over 6 years. Singapore Medical Journal December 2009. Volume 50 Issue 12
    Tan KK, Yan ZY, Vijayan A, Chiu MT
  • Case report: Emergency Surgery for a ruptured intra-abdominal desmoid tumour. Annals of Medicine Singapore. April 2010
    Tan KK, Yan ZY, Liau KH

Research Trials