Dr Daniel Chan Wei Keong

Dr Daniel Chan graduated from Yong Loo Lin School of Medicine, National University of Singapore, in 2012. He underwent Paediatric Residency training in KK Women’s and Children’s Hospital, and Singapore General Hospital. During his Paediatric Residency, he served as the Chief Resident from 2019-2020.

As a paediatric endocrinologist, his special interests include hypothalamo–pituitary disorders, both congenital and acquired, and neonatal endocrinology, with a focus on optimising early-life hormonal and metabolic health to improve long-term cardiometabolic outcomes. He was awarded the Health Manpower Development Plan Award in 2024 and completed a Clinical Fellowship in Paediatric Endocrinology at Great Ormond Street Hospital, London, United Kingdom.

He aims to drive clinical and research collaborations in maternal and child health, bridging neonatology, obstetrics and gynaecology, and paediatrics. Additionally, he maintains a deep commitment to medical education at both undergraduate and postgraduate levels, mentoring medical students, junior residents, and senior residents.

Research Interests: Hypothalamo-pituitary disorders, neonatal endocrinology, hyperinsulinism, population health.

• Masters of Clinical Investigation, Yong Loo Lin School of Medicine, National University of Singapore (2025)
• Membership of the Royal College of Paediatrics and Child Health (MRCPCH, UK) (2018)
• Master of Medicine (Paediatrics) (Singapore) (2018)
• MBBS, Yong Loo Lin School of Medicine, National University of Singapore (2012)

• Consultant, Endocrinology Service, Department of Paediatrics, KK Women’s & Children’s Hospital (2023 – Present)
• Clinical Fellow, Department of Endocrinology, Great Ormond Street Hospital, London, United Kingdom (2025)
• Associate Consultant, Endocrinology Service, Department of Paediatrics, KK Women’s & Children’s Hospital (2021 – 2022)
• Clinical Assistant Professor, Duke-NUS Medical School
• Clinical Lecturer, Yong Loo Lin School of Medicine
• Clinical Tutor, Lee Kong Chian School of Medicine
• Clinical Tutor, Alice Lee Centre for Nursing Studies
• Associate Faculty, Singapore University of Social Sciences
• SingHealth Associate in Education
• Faculty and Resident Mentor, SingHealth Paediatrics Residency

• Paediatric Academic Clinical Programme (Tan Cheng Lim) Award (Co-investigator, 2026)
• Singapore Health Quality Service Award – Gold (2025)
• Paediatric Academic Clinical Programme (Tan Cheng Lim) Award (Mentor, 2025)
• Nurturing Clinician Scientist Award (Principal Investigator, 2024)
• SingHealth Duke-NUS Academic Medicine Research Grant (Transition Project) (Principal Investigator, 2024)
• SingHealth Duke-NUS Academic Medicine Strategic Research Grant (Co-investigator, 2023)
• National Medical Research Council Research Training Fellowship (2023)
• KK Women’s and Children’s Hospital Academic Medicine Start Up Grant (Principal Investigator, 2022)
• Health Manpower Development Plan Award - Great Ormond Street Hospital (2024)
• Outstanding Faculty Award (2024)
• Outstanding Resident Award (2013, 2020)
• SingHealth Inspiring Educator Award (2020)
• Best Resident Teacher Award (2020)
• Best Senior Resident, Neonatology (Singapore General Hospital) (2019)
• Singapore Health Quality Service Award – Silver (2018)
• Service from the Heart Award (2017)

• Digital Health Interventions in Children and Adolescents with Type 1 Diabetes Mellitus and their Impact on Clinical and Behavioral Outcomes: A Scoping Review.
  E Beh, JY Lin, PY Loh, EJ Poh, G Leong, D Chan. JMIR Mhealth Uhealth. 2026 Mar 2;14:e79338.
• From Standard to Individualized Diazoxide Therapy in Congenital Hyperinsulinism: A Narrative Review
  T Wong, D Chan, C Chua, WQ Cher, S Lim, S Chandran, F Yap. Frontiers in Pharmacology, March 2026
• Consensus statement on Singapore guidelines for feeding and eating in infants and young children
  D Chan, CS Ong, SL Loy, CW Ku, JY Lin, BKG Loo, YB Tan, N Tan, D Ravichandran, M Tan, PL Quah, C Lim, M Pandi, WZ Leo, PL Ooi, KT Low, WM Han, MF Chong, FK Chiou, ASM Chang, M Aw, VS Raj, KH Tan, F Yap, MC Chua. Singapore Med J. March 2026
• Parental Quality of Life and Its Influence on Health-Related Quality of Life in Children with Type 1 Diabetes: A Cross-Sectional Dyadic Study in a Multi-ethnic Cohort.
  JY Lin*, D Chan*, ST Lim, W Low, RF Vasanwala. BMC Endocr Disord. 2026 Jan 3;26(1):29.
  Indicates co-first authors
• Artificial intelligence-driven anthropometric assessment for young children: Evaluating the accuracy and practicality of a digital image-based length and weight prediction tool.
  D Chan, MC Chua, M Hadimaja, S Mukherjee, J Wong, F Yap. BMJ Health Care Inform. 2025 Dec 9;32(1):e101540.
• The Reported Late Effects Experienced by Childhood Cancer Survivors Treated in Singapore: A Clinical Audit.
  JSL Lam, K Leong, DJL Tan, ASH Tan, MM John, D Chan, BR Ma, P Iyer, SY Soh, AM Tan, RF Vasanwala, M Seng. Ann Acad Med Singap. 2025 Nov;54:11.
• Efficacy of a Mobile App-Based Intervention to Improve Eating Behaviours and Lifestyle in Infants of Mothers with Metabolic Risk Factors: Study Protocol of a Randomized Controlled Trial.
  D Chan, K Leong, CS Ong, CW Ku, JKY Chan, MC Chua, F Yap, SL Loy. BMJ Open. 2025 Sep 30;15(9):e101684.
• Breastfeeding and its Impact on Glucose Trends and Hypoglycemia Risk in At-risk Neonates: A Prospective Observational Study.
  D Chan, S Chandran, MC Chua, RT Zheng, F Yap. J Paediatr Child Health. 2025 Sep 3.
• Comparative analysis of an automated bone age tool with manual assessment in a multiethnic Southeast Asian paediatric cohort in Singapore.
  D Chan, CHN Tan, PV Cheah, N Lee, L Toh, PH Tang, M Arjandas, RF Vasanwala. Pediatr Radiol. 2025 Aug 28.
• Glucose Levels in At-risk Newborns (GLEAN): A Prospective Cohort Study on Glucose Profiles in Infants at Risk of Hypoglycaemia.
  F Yap*, D Chan*, RT Zheng, LS Bos, VS Rajadurai, S Chandran. Front Endocrinol (Lausanne). 2025 Aug 8;16:1599366.
  Indicates co-first authors
• SOX2 Variant Resulting in Hypogonadotropic Hypogonadism, Learning Difficulties and Ear (Rather Than Eye) Anomalies.
  WQ Cher, D Chan. JCEM Case Rep. 2025 Jun 10;3(7):luaf126.
• Approach to Premature Thelarche in Children.
  Wen Hann Chow, KX Zhang, D Chan. Singapore Med J. 2025 Jun 1;66(6):338-342.
• Vitamin D Deficiency and Clinical Outcomes in Critically Ill Paediatric Patients: A Systematic Review and Meta-Analysis.
  N Tan, B Yeo, R Sultana, RF Vasanwala, JH Lee, D Chan. Journal of the Endocrine Society, Volume 9, Issue 5, May 2025
• Development and validation of a novel self-assessment tool for breastfeeding mothers
  CS Ong, SL Loy, C Pang, S Lee, S Krishnan, JT Tan, D Chan, CW Ku, JKY Chan, F Yap, MC Chua. Int Breastfeed J. 2025 Apr 3;20(1):25
• Caregiver feeding practices and eating behaviours in infants and toddlers in Singapore
  PL Quah*, D Chan*, SL Loy, CS Ong, MC Chua, F Yap, N Tan, M Chia, T Chua, KH Tan. Front. Nutr. 2025 Mar 12:1540031
  *Indicates co-first authors
• Development and psychometric validation of a clinical instrument for infant feeding and lifestyle evaluation.
  D Chan, JY Lin, R Zheng, CS Ong, CW Ku, Benny Loo, JKY Chan, MC Chua, F Yap, SL Loy. J Pediatr Gastroenterol Nutr. 2025 Feb 11
• Delayed Puberty and Incidental Hypertension in a 14-year-old Girl.
  D Chan, PV Cheah, XY Chin, Vasanwala RF. Pediatr Rev. 2024 Dec 1;45(12):712-717
• Spontaneous regression of paediatric pituitary lesions - report of 2 cases and literature review.
  JM Esguerra, D Chan, PH Tang, N Lek, S Low. Child’s Nervous Syst. 2024 Nov 27;41(1):6
• Exploring the Use of a Length Artificial Intelligence (LAI) Algorithm to Estimate Children’s Length from Smartphone Images in a Real-World Setting: A Proof-of-Concept Study
  MC Chua, M Hadimaja, J Wong, S Mukherjee, A Foussat, D Chan, U Nandal, F Yap. JMIR Pediatr Parent. 2024 Nov 22;7:e59564
• Comparative Analysis of INTERGROWTH-21st and Fenton Growth Charts for Birth Weight Classification in a multi-ethnic Asian cohort: A cross-sectional study.
  D Chan, R Zheng, E Beh, T Heng, S Chandran, F Yap. BMJ Paediatr Open. 2024 Nov 2;8(1):e002864
• Knowledge, Attitudes, and Practices of Paediatric Medical Officers and Registrars on the Developmental Origins of Health and Disease in a Tertiary Women’s and Children’s Hospital
  D Chan, T Heng, R Zheng, S Chang, SL Loy, CW Ku, MC Chua, F Yap. BMC Med Educ. 2024 Oct 7;24(1):1097
• Atypical presentations of primary acquired hypothyroidism – a case series.
  Pravin RR, Kan SY, Soh SY, D Chan, RF Vasanwala. Atypical presentations of primary acquired hypothyroidism - a case series. BMC Endocr Disord. 2023 Nov 6;23(1):242
• Evaluating the influence of low birth weight on food parenting practices in preschool children.
  Sng QW, Chong FFM, D Chan, Tan KH, He HG. Appetite. 2023 Sep 8:107031
• Monozygotic twins with identical premature timing of acne onset: A case report.
  A Tan, JY Lim, SY Chia, D Chan. The Australasian Journal of Dermatology, 10.1111/ajd.14117. 30 Jun. 2023
• Proactive steps to population health: Starting Early, Starting Right
  Chan. Ann Acad Med Singap Jun 2023;52:278-9
• Biodiversity and its double-edged role in the pathogenesis of type 1 diabetes mellitus
  D Chan, Jan Hau Lee. Lancet Diabetes Endocrinol. 2023 Apr;11(4):220-222
• Paediatric Obesity Evaluation for Metabolic Susceptibility (Retrospective cohort study)
  D Chan, C Chua, C Loh, R Sultana, RF Vasanwala. BMJ Open Diab Res Care 2023 Apr;11:e003228
• Metabolic health status and fecundability in a Singapore preconception cohort study.
  Loy SL, D Chan, Ku CW, Cheung YB, Godfrey KM, Tan KML, Chong YS, Shek LP, Tan KH, Chan SY, Chan JKY, Yap F. Am J Obstet Gynecol. 2021 Dec 16:S0002-9378(21)02684-3
• Neonatal hypoglycaemia – What’s Known and What’s New
  D Chan, DKL Chan. MIMS Journal of Paediatrics, Obstetrics and Gynaecology. 2020 Mar, Vol. 46 No. 1: 37-42
• Young girl with bruising: Finding the X factor.
  D Chan, J Lam. J Paediatr Child Health. 2019 Apr;55(4):465-467
• Calcium management challenges in a macrosomic child with subcutaneous fat necrosis.
  D Chan, Salas WM, F Yap, M Koh. BMJ Case Rep. 2019 Feb 19;12(2)
• Hypertensive urgency in nephrogenic diabetes insipidus with concomitant Hinman syndrome
  YG Tan, D Chan, F Yap, TL Yap. BMJ Case Reports CP 2019;12:e229095.
• Cushing’s disease presenting with pituitary apoplexy.
  D Chan, CR Teo, Dalan R. J Clin Neurosci. 2012 Nov;19(11):1586-9