Dr Mildrid Yeo Li Wen

About

Dr Mildrid Yeo completed her medical training at the University of Bristol, UK, in 2009 and underwent training in Paediatrics in the East Midlands, UK, at Queens Medical Centre Nottingham University Hospital NHS Trust and City Hospital. She successfully completed her specialist training in paediatric metabolic medicine at both Great Ormond Street Hospital and Evelina London Children’s Hospital, UK. She was appointed as a consultant in paediatric metabolic medicine at Great Ormond Street Hospital, UK, in July 2020 -July 2023 before joining the KK Women's and Children's Hospital's Genetics department as a consultant. Her interests are wide ranging in particular urea cycle disorders, organic acidaemia and aminoacidopathies. She is dual accredited by the General Medical Council, UK, in both general paediatric and paediatric metabolic medicine.

Education and Training

• FRCPCH (UK), 2022
• MRCPCH (RCPCH, UK), 2015
• MBcHB University of Bristol, UK, 2009
  

Professional Appointments and Committee Memberships

• Consultant, Department of Genetics, KK Hospital 2023- Present
• Consultant, Department of Paediatric Metabolic Medicine, Great Ormond Street Hospital, London, UK 2020-2023

Awards

• Paediatric academic clinical fellowship, National Institute of Health and Research UK 2011-2014

Research Interests

• Inborn errors of metabolism
• Gene therapy

Publications

• Clinical and molecular characterization of novel FARS2 variants causing neonatal mitochondrial disease. Chen W, Rehsi P, Thompson K, Yeo M, Stals K, He L, Schimmel P, Chrzanowska-Lightowlers ZMA, Wakeling E, Taylor RW, Kuhle B. Mol Genet Metab. 2023 Jul 24; 140 (3):107657
• Clinical experience with glycerol phenylbutyrate in 20 patients with urea cycle disorders at a UK paediatric centre. Mildrid Yeo, Preeya Rehsi, Megan Dorman, Stephanie Grunewald, Julien Baruteau, Anupam Chakrapani, Emma Footitt, Helen Prunty, Melanie McSweeney. JIMD Rep. 2023; Jul; 1-10.
• Natural history of epilepsy in argininosuccinic aciduria provides new insights into pathophysiology: a retrospective international study. Elkhateeb N, Olivieri G, Siri B, Boyd S, Stepien KM, Sharma R, Morris AAM, Hartley T, Crowther L, Grunewald S, Cleary M, Mundy H, Chakrapani A, Lachmann R, Murphy E, Santra S, Uudelepp ML, Yeo M, Bernhardt I, Sudakhar S, Chan A, Mills P, Ridout D, Gissen P, Dionisi-Vici C, Baruteau J. Epilepsia. 2023 Mar 30
• Disorders of carbohydrate metabolism: a review of glycogen storage disorders. Mildrid Yeo, Hager Moawad, Stephanie Grunewald. Paediatrics and Child Health. 2023; Volume 33 (13); 65-72
• Direct replacement of oral sodium benzoate with glycerol phenylbutyrate in children with urea cycle disorders. Mildrid Yeo, Preeya Rehsi, Megan Dorman, Stephanie Grunewald, Julien Baruteau, Anupam Chakrapani, Emma Footitt, Helen Prunty, Melanie McSweeney. JIMD Rep. 2022 Feb 2; 63(2):137-145.
• Expanding the phenotypic spectrum of ALDH18A1-related autosomal recessive cutis laxa with a description of novel neuroradiological findings. Pickwick, Charlotte; Callewaert, Bert; van Dijk, Fleur; Harris, Juliette; Wakeling, Emma; Hay, Eleanor; Yeo, Mildrid; Chakrapani, Anupam; Baptista, Juliaf,; Moore, Sandra; Yoong, Michael; Chatterjee, Fiona; Ghali, Neeti. Clinical Dysmorphology. 2022 Apr 1;31(2):66-70.
• Clinical utilisation of dried blood spot Nitisinone (NTBC) and succinylacetone (SA) concentrations in hereditary tyrosinaemia type 1- a UK centre experience. Yeo M, Turner C, Dalton RN, Rahman Y, Vara R. Ann Clin Biochem. 2020 Nov; 57(6): 412-419.
• Classical Galactosaemia and Bone Mineral Density. Yeo M, Jose Rodriguez Ciancio, Sirisha Penumatsa, Lorenzo Biassoni, Caroline Brain, and Stephanie Grunewald. Ann of Paediatrics and Child Health. 2020; 8(8): 1203.
• What are the information needs of parents caring for a child with Glutaric aciduria type 1? Piercy, H., Yeo, M., Yap, S. et al. BMC Pediatr. 2019; Oct 13;19(1):349. 19, 349.
• Hyperammonaemia- A guide for clinicians. M.Yeo, E.Neil, R.Vara. 2018 (Orphan Europe Recordati Group)
• Neonatal head and torso vibration exposure during inter-hospital transfer. Blaxter L, Yeo M, McNally D, Crowe J, Henry C, Hill S, Mansfield N, Leslie A, Sharkey D. Proc Inst Mech Eng H. 2017; Feb; 231(2):99-113.
• Paediatric Pancreatitis. M.Yeo and S. Kirkham. Paediatric and Child Health. 2017; Volume 27 (12); 561-566.