Renin Activity, plasma

XU0109

Synonym(s):
Specimen Container
EDTA tube
Specimen Requirement
Whole Blood
EDTA 4 - 6mL
Specimen Storage/Transport
Place specimen in a biohazard specimen bag and immerse this bag in crushed ice. Send immediately to lab.
 
To spin and separate the plasma and store at – 20°C before the next transport is available.
Orderable as Urgent? No
Turn Around Time
2 – 4 weeks
Reference Value(s)
0 – 2 years: 4.6 ng/mL/hour (mean)* Range: 1.4-7.8 ng/mL/hour
3 – 5 years: 2.5 ng/mL/hour (mean)* Range: 1.5-3.5 ng/mL/hour
6 – 8 years: 1.4 ng/mL/hour (mean)* Range: 0.8-2.0 ng/mL/hour
9 – 11 years: 1.9 ng/mL/hour (mean)* Range: 0.9-2.9 ng/mL/hour
12 – 17 years: 1.8 ng/mL/hour (mean)* Range: 1.2-2.4 ng/mL/hour
 
*Mean data not standardized as to time of day or diet. Infants were supine, children sitting.

Na-depleted, upright (peripheral vein specimen)
18 – 39 years: 10.8 ng/mL/hour (mean) 2.9 – 24.0 ng/mL/hour (range)
> or =40 years: 5.9 ng/mL/hour (mean) 2.9 – 10.8 ng/mL/hour (range)

Na-replete, upright (peripheral vein specimen)
18 – 39 years: 1.9 ng/mL/hour (mean) < or =0.6 – 4.3 ng/mL/hour (range)
> or =40 years: 1.0 ng/mL/hour (mean) < or =0.6 – 3.0 ng/mL/hour (range)
Testing Laboratory Location NUH
Laboratory Mayo Medical Laboratories in Rochester
Contact Number 6394 1352
Day and Time Performed
Mon – Fri 0800 hrs– 1700 hrs
Sat 0800 hrs – 1230 hrs
Orderable on CPOE? Yes
Downtime Form

Clinical Chemistry - Form A

Additional Information

The plasma renin activity cannot be interpreted if the patient is being treated with spironolactone (Aldactone). Spironolactone should be discontinued for 4 to 6 weeks before testing.

Change History Notes

  • 22 Jul 2025 03:00 PM

    Added image of ice pack.

  • 12 Aug 2021 12:00 AM

    Updated Additional Information.

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Last Updated - 24 Jul 2025