Sweat chloride test, Sweat

BC6501

Synonym(s):
Specimen Container Plain microtube (200uL)
(Refer to Sweat test collection-service code VR0030)
Specimen Requirement

The sweat test is offered only to patients at an appropriate criterion: to increase the likelihood of collecting an adequate sweat specimen, sweart chloride testing can be evaluated in asymptomatic newborns with a positive newborn screen result or positive prenatal genetic test when the infant is at least ten days old, greater than 36 weeks gestation, and weighs >2kg. Sweat chloride testing should be performed as soon as possible at or after 10 days of age life, ideally by four weeks of age. Sweat collections acquired in newborns >3.5kg (versus >2kg) improve specimen acceptability rates by 25% and should be considered when assessing the risk of a quality not sufficient (QNS) collection versus the need to obtain diagnostic information. 

Sweat minimum volume: 50 uL

Specimen Storage/Transport

Send specimen directly to the laboratory.
Store sample at room temperature.

Orderable as Urgent? No
Turn Around Time

1 working day

Reference Value(s)

Sweat Chloride Reference Range (mmol/L)


Cystic Fibrosis unlikely
Intermediate​​Indicative of Cystic Fibrosis
​Chloride
<=29​
​30 to 59
​>=60


Testing Laboratory Location

KKH

Laboratory Biochemical Genetics Lab
Contact Number

6394 5049

Day and Time Performed

Wednesday: 0900 hrs - 1200 hrs
Thursday: 1300 hrs - 1700 hrs

Orderable on CPOE? Yes (Temporary No till further notice)
Downtime Form

Biochemical Genetics Lab

Additional Information
Useful For​
  • Sweat chloride measurements are used in the diagnosis of Cystic Fibrosis.

Change History Notes

  • 19 Jul 2024 01:00 PM

    Updated Specimen requirement and Reference Value(s).

  • 15 Feb 2023 12:00 AM

    ​Updated Orderable on CPOE.

  • 11 Jan 2023 12:00 AM

    ​New test.

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Last Updated - 05 Apr 2025