Thiopurine S-Methyltransferase (TPMT) and Nudix Hydrolase 15 (NUDT15) Genotyping

IM0026

Synonym(s):
Specimen Container

​EDTA tube

Specimen Requirement

Whole Blood EDTA
Adult: 6 mL
Paediatric: 3 mL

Specimen Storage/Transport

Refrigerate sample until transfer to laboratory. Do not freeze. Sample should reach the laboratory as soon as possible, preferably within 72 hours after collection.

Orderable as Urgent? No
Turn Around Time

1 – 3 days

Testing Laboratory Location

​TTSH

Laboratory Molecular Diagnostic Laboratory
Contact Number

6394 1352

Day and Time Performed

Mon - Fri: 0800 hrs to 1700 hrs
Sat: 0800 hrs to 1200 hrs

Orderable on CPOE? No
Downtime Form

Clinical Chemistry - Form A

Additional Information

This assay tests for TPMT *3 (c.460G>A, c.719A>G) and NUDT15 (c.415C>T) to aid prediction for toxicity to thiopurine drugs.

Change History Notes

  • 30 Dec 2021 12:00 AM

    New test.

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Last Updated - 27 May 2025