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Thiopurine S-Methyltransferase (TPMT) and Nudix Hydrolase 15 (NUDT15) Genotyping

Test Code:

IM0026

Synonym(s):

Specimen Container

​EDTA tube

Specimen Requirement

Whole Blood EDTA
Adult: 6 mL
Paediatric: 3 mL

Specimen Storage / Transport

Refrigerate sample until transfer to laboratory. Do not freeze. Sample should reach the laboratory as soon as possible, preferably within 72 hours after collection.

Method

 

Orderable as STAT?

No

Turn Around Time

1 – 3 days

Reference Value(s)

Testing Laboratory Location

​TTSH

Laboratory

Molecular Diagnostic Laboratory

Contact Number

6394 1352

Day and Time Performed

Mon - Fri: 0800 hrs to 1700 hrs
Sat: 0800 hrs to 1200 hrs

Orderable on CPOE?

No

Additional Information

This assay tests for TPMT *3 (c.460G>A, c.719A>G) and NUDT15 (c.415C>T) to aid prediction for toxicity to thiopurine drugs.

Change History Notes

Others

Keywords

Thiopurine S-Methyltransferase (TPMT) and Nudix Hydrolase 15 (NUDT15) Genotyping IM0026
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