Urinary GAG Electrophoresis (Mucopolysaccharide Disorders - includes GAGs quantitation and 2D electrophoresis)

BC6090

Synonym(s):
Specimen Container
Wide mouth sterile container
Specimen Requirement
Urine
5 mL - 10 mL
Specimen Storage/Transport
Fresh urine, free from bacterial contamination and no preservative. Please send with a separate ice pack.
Orderable as Urgent? No
Turn Around Time
3 weeks
Testing Laboratory Location KKH
Laboratory Biochemical Genetics lab
Contact Number 6394 8728
Day and Time Performed
Mon – Fri: 0900 hrs – 1800 hrs
Last specimen reciept time is at 1730 hrs.
Orderable on CPOE? Yes
Downtime Form

Biochemical Genetics Lab

Additional Information
Useful For​Screening of mucopolysaccharide disorders (MPS). Testing includes low voltage electrophoresis in two dimensions on cellulose acetate sheets followed by a staining process with Alcian Blue.

Mucopolysaccharidoses (MPS) are a group of inherited diseases which are characterized by a progressive accumulation of partially degraded glycosaminoglycans (GAGs) in the lysosomes.
Clinical Indication​
  • skeletal deformities
  • hepatomegaly
  • Hernia
  • learning difficulties
  • behavioural disturbance and severe bone dysplasia
​Interpretation Inte​rpretation is based on the overall pattern of the electrophoresis profile. Diagnosis would need to be confirmed by enzyme or DNA analysis.

 

For URGENT analysis, contact the Biochemical Genetics laboratory at 6394 8728 or the Lead Scientist at 8388 8741 to discuss.
 
If sent after office hours, urine will be stored in Clinical Laboratory -20°C freezer.

Last Updated - 28 May 2025