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Clin Assoc Prof Joyce Lam Ching Mei

Clin Assoc Prof Lam Ching Mei Joyce

MBBS, MMed (Paeds), MRCPCH (UK), FRCPA, FAMS

Senior Consultant

KK Women's and Children's Hospital

Specialty: Paediatric Haematology/Oncology, Pathology & Laboratory Medicine

Conditions Treated by this Doctor:
Children Cancer, Clotting and Bleeding Disorder, Diagnostic Haematology, Paediatric Cytopaenias.

Clinical Appointments

  • Senior Consultant Haematology/Oncology Service KK Women's and Children's HospitalKK Women's and Children's Hospital
  • Head of Service​, Haematology Laboratory and Blood Bank Department of Pathology and Laboratory Medicine KK Women's and Children's HospitalKK Women's and Children's Hospital
  • Senior Consultant SingHealth Duke-NUS Blood Cancer Centre

Profile

Dr Joyce Lam Ching Mei is a Senior Consultant Haematologist and Head of the Haematology Laboratory and Blood Bank at KK Women’s and Children’s Hospital. She has expertise in diagnostic haematology, cytopaenias, bleeding and clotting disorders in children and general paediatric oncology. Her research interests include outcome-based assessments in haemophilia, long-term clnical outcomes in thalassaemia and anticoagulation strategies in extracorporeal membrane oxygenation. She is the Primary Investigator for a number of clinical trials in paediatric haemophilia and anticoagulation. She is also actively involved in undergraduate and postgraduate medical education.

Education

  • FRCPA 2013
  • MMed (Paeds) 2004
  • MRCPCH 2004
  • MBBS 2000

Professional Appointments and Committee Memberships

  • Senior Clinical Lecturer, NUS Yong Loo Lin School of Medicine
  • Adjunct Assistant Professor, Duke-NUS Medical School
  • Clinical Teacher, Lee Kong Chian Medical School
  • Senior Consultant, Paediatric Haematology/Oncology Service, Department of Paediatric Subspecialties
  • Head, Haematology Laboratory and Blood Bank Service, Department of Pathology and Laboratory Medicine
  • Fellow, Academy of Medicine, Singapore
  • Ex-Co Member, Asia-Pacific Haemophilia Working Group
  • Ex-Co Member, Singapore Society of Haematology
  • Member, Asia-Pacific Society of Thrombosis and Haemostasis
  • Member, International Society of Thrombosis and Haemostasis
  • Member, World Federation of Haemophilia
  • Member, Paediatric Oncology Group Singapore

Awards

  • Singapore Health Quality Service Award, Silver (2018)
  • Best Poster Prize (Clinical Research Category), 9th KKH Annual Scientific Meeting (2017)
  • Yong Loo Lin School of Medicine Deans Award for Teaching Excellence (2016)
  • Singapore Health Quality Service Award, Silver (2014)
  • Service from the Heart Award (2013)
  • Long Service Award (2012)
  • Human Manpower Development Plan (HMDP) Award from Ministry of Health for 1-year fellowship in Clinical and Laboratory Haematology (2010)
  • RCPA QAP Prize for Best Poster Presentation, RCPA Pathology Update (2010)
  • Merit Award in Free Paper Competition, 2nd KKH Annual Scientific Meeting (2006)

Research Interests

  • Neurocognitive and social outcomes from acute lymphoblastic leukaemia (ALL) treatments
  • Epidemiology of bleeding disorders in children
  • Pharmacokinetic studies of aprepitant in paediatric and adolescent cancer patients
  • Cross-sectional study on the clinical and social outcomes of transfusion dependent Thalassaemia patients in Singapore

Publications

  • PRINCIPLES OF HAEMOPHILIA CARE: THE ASIA-PACIFIC PERSPECTIVE. Dunkley S, Lam JCM, John MJ, Wong RSM, Tran H, Yang R, Nair SC, Shima M, Street A, Srivastava A. for the Asia-Pacific Haemophilia Working Group (APHWG). Haemophilia 2018; DOI:10.1111/hae.13425
  • ANTICOAGULATION IN EXTRACORPOREAL MEMBRANE OXYGENATION. Judith Ju-Ming Wong, Joyce Ching Mei Lam, Yee Hui Mok, Jan Hau Lee. Journal of Emergency and Critical Care Medicine. Feb 2018; DOI: 10.21037/jeccm.2018.01.12
  • A RARE CASE OF ANTENATAL HEMORRHAGIC STROKE AND RECURRENT PURPURA FULMINANS IN A PRETERM NEWBORN. Ang IWL, Chan DKL, Lam JCM, Shah VA. NeoReviews Feb 2018; 19(2) e104-e108; DOI: 10.1542/neo.19-2-e104
  • WORKING TOGETHER ON TRANSFUSION AUDITS TO IMPROVE CLINICAL PRACTICE. Zhong X, Heng, ML, Lam JCM. ISBT Science Series 2018, DOI:10.1111/voxs.12407
  • THE BOY WITH THE RUDDY FACE: AN APPROACH TO POLYCYTHAEMIA PRESENTING IN CHILDHOOD – Lam JCM, Campbell S, Barnes C. Journal of Paediatrics and Child Health December 2017, DOI:10.1111/jpc.13820
  • LEUKAEMIA CUTIS OF THE SCALP - Rui K, Mei Yoke C, Yee L, Lam JCM. Archives of Disease in Childhood 2017, DOI:10.1136/archdischild-2017-313284
  • EPISODIC REPLACEMENT OF CLOTTING FACTOR CONCENTRATES DOES NOT PREVENT BLEEDING OR MUSCULOSKELETAL DAMAGE – THE MUSFIH STUDY - P. Poonnoose, JDA Carneiro, AL Cruickshank, M El Ekiaby, RP. Perez Bianco, MC Ozelo, N De Bosch, M. Baghaipour, SL L Tien, A Chuansumrit, EA D’amico, A Van Zyl, A Sabour, M Candela, JBS Ricciardi, A Ruiz-S Aez, R. Ravanbod, JCM Lam, S Jaovisidha, ML Kavitha, S Gibikote, N Shyamkumar, A. Srivastava. Haemophilia 2017; DOI: 10.1111/hae.13242
  • MANAGEMENT OF A KAPOSIFORM HAEMANGIOENDOTHELIOMA OF THE KIDNEY WITH KASABACH-MERITT PHENOMENON WITHOUT CHEMOTHERAPY - Nwe MS, Ong MW, Lam JCM, Chang KT-E, Fortier MV, Wijeweera O, Tan AM, Loh AHP. Pediatric Hematology Oncology Journal 2017, doi:10.1016/j.phoj.2017.03.001
  • CAUSATIVE PATHOGENS OF FEBRILE NEUTROPAENIA IN CHILDREN TREATED FOR ACUTE LYMPHOBLASTIC LEUKAEMIA - Joyce CM Lam, Jie Yang Chai, Yi Ling Wong, Natalie WH Tan, Christina TT Ha, Mei Yoke Chan, Ah Moy Tan. Annals Academy of Medicine Singapore 2015;44:530-4
  • A COMPREHENSIVE STUDY OF CURRENT HAEMOPHILIA CARE AND OUTCOMES IN SINGAPORE – HJ Ng, J Lam, PL Koh, L Ho, CY Lim, M Akhbar Ali, D Mya, H Than, LP Ho, AM Tan. LH Lee, SL Tien. Haemophilia 2015; 21(5):e428-431
  • RAPID-ONSET OBESITY WITH HYPOTHALAMIC DYSFUNCTION, HYPOVENTILATION, AND AUTONOMIC DYSREGULATION (ROHHAD) SYNDROME MAY HAVE A HYPOTHALAMUS – PERIAQUEDUCTAL GRAY LOCALIZATION – C Chow, MV Fortier, L Das, AP Menon, R Vasanwala, Joyce CM Lam, ZM Ng, SR Ling, DWS Chan, CT Choong, WKM Liew, T Thomas. Pediatric Neurology 2015; 52(5):521-5
  • CONGENITAL GATA1-MUTATED MYELOPROLIFERATIVE DISORDER IN TRISOMY 21 COMPLICATED BY PLACENTAL FETAL THROMBOTIC VASCULOPATHY – Tracy J.Z. Loh, Derrick W.Q. Lian, Prasad Iyer, Joyce C.M. Lam, Chik H. Kuick, Aye C.L. Aung, Kenneth Tou En Chang. Human Pathology 2014; 45: 2364–2367
  • DIAGNOSIS AND MANAGEMENT OF IRON DEFICIENCY ANAEMIA IN CHILDREN — A CLINICAL UPDATE – EC Chew, Lam JCM. Proceedings of Singapore Healthcare. 21(4): 278-85
  • INTESTINAL ATRESIA OCCURRING IN ASSOCIATION WITH PLACENTAL FETAL THROMBOTIC VASCULOPATHY: A CASE REPORT WITH LITERATURE REVIEW – Lian DQ, Lam JCM, Aung AC, Li FX, Chang TE. Pediatric and Developmental Pathology. 2013; 16(1):28-31
  • SKIN MANIFESTATION OF STENOTROPHOMONAS MALTOPHILIA INFECTION – A CASE REPORT AND REVIEW ARTICLE – Teo WY, Chan MY, Lam CM, Chong CY. Annals of the Academy of Medicine Singapore. Dec 2006; 35 (12):897-900
  • WHEN IS A MEDIASTINAL MASS CRITICAL IN A CHILD: AN ANALYSIS OF 29 PATIENTS – JCM Lam, CH Chui, AS Jacobsen, AM Tan, VT Joseph. Paediatric Surgery International, March 2004; 20 (3): 180-4

Research Trials

  • PROTECT VIII - A Phase II / III Multicentre, Partially Randomised, Open Label Trial Investigating Safety and Efficacy of On-Demand and Prophylactic Treatment with BAY94-9027 in Severe Haemophilia A – Site PI
  • PROPEL - Phase 3, Prospective, Randomized, Multi-center Clinical Study Comparing the Safety and efficacy of BAX 855 following PK-guided Prophylaxis Targeting two different FVIII Trough Levels in Subjects with Severe Hemophilia A – Site PI
  • Phase 3, prospective, multi-center, open label study to investigate safety,immunogenicity and hemostatic efficacy of PEGylated Factor VIII (BAX 855) in previously untreated patients (PUPs) < 6 years with severe hemophilia A (FVIII < 1%) – Site PI
  • A Phase 3, open-label, randomized, multi-center, controlled trial to evaluate the pharmacokinetics and pharmacodynamics of edoxaban and to compare the efficacy and safety of edoxaban with standard of care anticoagulant therapy in pediatric subjects from birth to less than 18 years of age with confirmed venous thromboembolism (VTE) – Site PI
  • EINSTEIN Junior - Multicenter, open-label, active-controlled, randomized study to evaluate the efficacy and safety of an age-and body weight-adjusted rivaroxaban regimen compared to standard of care in children with acute venous thromboembolism – Site PI