The KKH Department of Pathology and Laboratory Medicine is an ISO-accredited laboratory for medical laboratory testing since 2003. With a team of over 100 highly trained staff, including histopathologists, clinical pathologists, medical laboratory scientists and medical technologists, the department offers comprehensive and reliable diagnostic service.

The laboratory is widely computerised, and with the Laboratory Information System interconnected to the hospital IT system, doctors are able to access or share test results with patients at the clinics or wards in a timely manner.

The department is accredited by the Singapore Accreditation Council for its laboratory services as well as the Royal College of Pathologists of Australasia for the training of residents in Anatomical Pathology, Microbiology and Chemical Pathology.